Dissection of the Common Carotid Artery and Internal/External Branching
2:53
Preparation of the CCA for the MCAO Suture Insertion
3:51
Middle Cerebral Artery Occlusion
5:59
Reperfusion
7:07
Results: Characteristics of Brain Tissue Following Ischemia-Reperfusion
8:38
Conclusion
Transcription
The overall goal of this surgical procedure is to officially and reliably induce Ischemic stroke while leaving the external cerebral artery intact. This method can help answer key questions in the field of stroke research, such as the impact of tr
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We describe a mouse model of stroke induced by the occlusion of the middle cerebral artery using a silicone coated suture. The protocol can be applied to induce permanent occlusion or a temporary ischemia, followed by reperfusion.