Characterization of Magnetic Device via Transport Measurements
4:00
Cellular MNP Uptake and Viability
5:26
Cell Differentiation and Growth on Magnetic Platform
7:04
Results: MNP-loaded PC12 Cells on Magnetic Devices
9:10
Conclusion
Transcription
Our approach makes it possible to control neural network formation using magnetic manipulations. This is an effective tool for in vitro studies of networks and offers novel therapeutic direction for biointerfacing devices. With this technique we c
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This work presents a bottom-up approach to the engineering of local magnetic forces for control of neuronal organization. Neuron-like cells loaded with magnetic nanoparticles (MNPs) are plated atop and controlled by a micro-patterned platform with perpendicular magnetization. Also described are magnetic characterization, MNP cellular uptake, cell viability, and statistical analysis.