Preparation of Reagents and Materials for Optimizing the Radiosynthesis of [18F]Fallypride
3:11
Parallel Synthesis of [18F]Fallypride with Different Precursor Concentrations
6:02
Synthesis Analysis to Determine Reaction Performance and Optimal Conditions
8:55
Results: Influence of Precursor Concentration on the Microdroplet Synthesis of [18F]Fallypride
10:08
Conclusion
Transcription
Current automated radio synthesizers are designed to produce large batches of widely used radiopharmaceuticals, such as FDG. Due to the limited number of syntheses possible per day, and relatively high reagent consumption, these systems, however,
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This method describes the use of a novel high-throughput methodology, based on droplet chemical reactions, for the rapid and economical optimization of radiopharmaceuticals using nanomole amounts of reagents.