Procedure: Collection of Blood from a Homologous Mouse Donor
3:25
Procedure: Animal Preparation
4:21
Procedure: SAH Induction
6:18
Post-surgery Procedure
6:42
Second Day of Surgery
7:38
Representative Results
9:51
Conclusion
Trascrizione
The overall goal of this present video is to explain the protocol of a double direct injection of blood into the cisterna magna as a model of subarachnoid hemorrhage. The physiology of the subarachnoid hemorrhage is often due to a rupture of an an
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We described in this protocol a standardized subarachnoid hemorrhage (SAH) mouse model by a double injection of autologous whole-blood into the cisterna magna. The high degree of standardization of the double-injection procedure represents a middle-to-acute model of SAH with relative safety regarding mortality.