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Pooled shRNA Screen for Reactivation of MeCP2 on the Inactive X Chromosome

7.2K Views

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11:15 min

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March 2nd, 2018

DOI :

10.3791/56398-v

March 2nd, 2018

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7,175 Views

Vid Leko¹^,², Smitha Sripathy¹, Robin L. Adrianse¹, Taylor Loe¹, Angela Park¹, Uyen Lao¹, Eric J. Foss¹, Marisa S. Bartolomei³, Antonio Bedalov¹^,⁴

¹Clinical Research Division, Fred Hutchinson Cancer Research Center, ²Hematology Branch, National Heart, Lung and Blood Institute, National Institutes of Health, ³Epigenetics Program, Department of Cell and Developmental Biology, University of Pennsylvania Perelman School of Medicine, ⁴Departments of Medicine and Biochemistry, University of Washington

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Pooled ShRNA Screen

MeCP2

Inactive X Chromosome

Mouse Tendon Fibroblasts

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