Name: bedside ultrasound for guiding fluid removal in patients with pulmonary edema: the reverse-falls protocol
Uploaded: 2018-07-28T13:00:00.000+00:00
Duration: 7 min 59 s
Description: Watch this Scientific Journal Video about Bedside Ultrasound for Guiding Fluid Removal in Patients with Pulmonary Edema: The Reverse-FALLS Protocol at JoVE.com

著者博士ポール Zamudio、この原稿への彼の貢献のため腎臓と重要なケアの専門家を確認したいです。

1. 利尿する前に血管外区画評価: 胸部超音波
<ol><li>低周波のフェイズド アレイ プローブを使用します。</li>
	<li>画面マーカー演算子左 (腹部や肺) 適切なマシンの設定を選択します。</li>
	<li>8-12 cm に深さを調整します。</li>
	<li>患者を仰臥位または半横臥位置に配置し、前胸部を公開します。患者の前胸部に 90 ° の角度で頭の方に直面してプローブ マーカーで探触子を配置します。<ol>
<li>4 つの場所の合計のための胸のそれぞれの側に 2 つの場所で鎖骨中央線上でこのプロトコルを実行: 2nd-3rdや 3rd-4番目の肋間スペース、4th-5番目または 5番目の6番目の肋間スペース。</li>
		<li>存在する場合は、B ラインを可視化します。 注: B ライン胸膜線上では、元の狭い高エコー アーティファクトで同期的に呼吸の動き (図 1) に移動です。</li>
	</ol>
</li>
	<li>肺浮腫の程度を定量化する各スキャン平面内の B ラインの数をカウントします。 注: 1 B 線までは正常です。2 ~ 3 B ラインを表し B 行の 4 以上が重度の浮腫に中等度を表す軽度の肺水腫A ラインとホワイト アウトのパターンは、非常に重篤な肺浮腫 (図 2) を表します。</li>
</ol>2 下大静脈超音波の利尿する前に血管内のコンパートメントを評価:
<ol><li>低周波、フェイズド アレイ プローブを使用します。</li>
	<li>画面マーカーのオペレーター権限を持つ心臓のマシン設定を選択し、最適な画像の解像度の 12-21 cm に深さを調整します。</li>
	<li>患者を仰臥位にし、前胸部を公開します。プローブ マーカーが頭の方に直面している患者さんの剣サブ領域に 90 ° の角度で探触子を配置します。<ol>
<li>傾いている正中線のすぐ右側に位置する探触子でこのプロトコルを実行少し右横と頭の方。</li>
		<li>右から左をスキャンすることによって、下大静脈と大動脈を視覚化します。</li>
		<li>目的はその縦平面でカーヴォ心房の接合部、横隔膜、肝臓、肝静脈、下大静脈を視覚化することに注意してください。大動脈、スキャン面を内側に angulating によって可視化される (図 3)。</li>
	</ol>
</li>
	<li>下大静脈とカーヴォ心房の接合部を特定したら、超音波を下大静脈の前後径を測定する M モードに設定します。<ol>
<li>タッチ ・ パッドを使用して、近く直交] セクションでは、目に見える肝静脈を指し示すカーヴォ心房の接合部に 2-4 cm に対応する M モードのビームを選択します。</li>
		<li>2 回目の M モード ボタンを選択し、M モード読書の少なくとも 1 の呼吸サイクル完了後画面がフリーズします。</li>
		<li>すべての測定、内部エッジを内部エッジから容器を測定機キャリパーを使用します。</li>
	</ol>
</li>
	<li>通常の呼吸サイクルの間に、d-max と D 分を測定します。</li>
</ol>3. 肺浮腫のグラデーションと下大静脈の直径に基づく流体管理目標を設定します。
<ol><li>利尿 (図 2) の必要性を決定するため肺超音波を評価します。</li>
	<li>利尿 (図 3) に耐えられるように患者さんの能力を決定する下大静脈超音波を評価します。</li>
</ol>4. 利尿療法を通して管外および血管コンパートメントを再評価します。
<ol><li>利尿剤治療の進捗状況を評価し、流体管理目標をガイド、6 時間ごとに上記としてプロトコルを繰り返します。</li>
</ol>

<ol>
	<li>Zoccali, C., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Pulmonary+congestion+predicts+cardiac+events+and+mortality+in+ESRD.">Pulmonary congestion predicts cardiac events and mortality in ESRD.</a> Journal of the Amerian Society of Nephrology. 24, 639-646 (2013).</li><li>Vitturi, N., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Lung+ultrasound+during+hemodialysis,+the+role+in+the+assessment+of+volume+status.">Lung ultrasound during hemodialysis, the role in the assessment of volume status.</a> International Urology and Nephrology. 46, 169-174 (2014).</li><li>Noble, V. E., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Ultrasound+assessment+for+extravascular+lung+water+in+patients+undergoing+hemodialysis.+Time+course+for+resolution.">Ultrasound assessment for extravascular lung water in patients undergoing hemodialysis. Time course for resolution.</a> Chest. 135, 1433-1439 (2009).</li><li>Lang, R. M., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Recommendations+for+Cardiac+Chamber+Quantification+by+Echocardiography+in+Adults:+An+Update+from+the+American+Society+of+Echocardiography+and+the+European+Association+of+Cardiovascular+Imaging.">Recommendations for Cardiac Chamber Quantification by Echocardiography in Adults: An Update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging.</a> Journal of the American Society of Echocardiography. 28, 1-39 (2015).</li><li>Barbier, C., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Respiratory+changes+in+inferior+vena+cava+diameter+are+helpful+in+predicting+fluid+responsiveness+in+ventilated+septic+patients.">Respiratory changes in inferior vena cava diameter are helpful in predicting fluid responsiveness in ventilated septic patients.</a> Intensive Care Medicine. 30, 1740-1746 (2004).</li><li>Feissel, M., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=The+respiratory+variation+in+inferior+vena+cava+diameter+as+a+guide+to+fluid+therapy.">The respiratory variation in inferior vena cava diameter as a guide to fluid therapy.</a> Intensive Care Medicine. 30, 1834-1837 (2004).</li><li>Lichtenstein, D. A. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Lung+ultrasound+in+the+critically+ill.">Lung ultrasound in the critically ill.</a> Annals of Intensive Care. 4, 1 (2014).</li><li>Lichtenstein, D. A. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=BLUE-Protocol+and+FALLS-Protocol:+Two+Applications+of+Lung+Ultrasound+in+the+Critically+Ill.">BLUE-Protocol and FALLS-Protocol: Two Applications of Lung Ultrasound in the Critically Ill.</a> Chest. 147, 1659-1670 (2015).</li><li>Moore, C. L., Copel, J. A. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Point-of-care+ultrasonography.">Point-of-care ultrasonography.</a> New England Journal of Medicine. 364, 749-757 (2011).</li><li>Lichtenstein, D., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=A-lines+and+B-lines:+lung+ultrasound+as+a+bedside+tool+for+predicting+pulmonary+artery+occlusion+pressure+in+the+critically+ill.">A-lines and B-lines: lung ultrasound as a bedside tool for predicting pulmonary artery occlusion pressure in the critically ill.</a> Chest. 136, (2009).</li><li>Trezzi, M., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Lung+ultrasonography+for+the+assessment+of+rapid+extravascular+water+variation,+evidence+from+hemodialysis+patients.">Lung ultrasonography for the assessment of rapid extravascular water variation, evidence from hemodialysis patients.</a> Internal and Emergency Medicine. 8, 409-415 (2013).</li><li>Lyon, M., Blaivas, M., Brannam, L. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Sonographic+measurement+of+the+inferior+vena+cava+as+a+marker+of+blood+loss.">Sonographic measurement of the inferior vena cava as a marker of blood loss.</a> American Journal of Emergency Medicine. 23, 45-50 (2005).</li><li>Katzarski, K. S., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=A+critical+evaluation+of+ultrasound+measurement+of+inferior+vena+cava+diameter+in+assessing+dry+weight+in+normotensive+and+hypertensive+hemodialysis+patients.">A critical evaluation of ultrasound measurement of inferior vena cava diameter in assessing dry weight in normotensive and hypertensive hemodialysis patients.</a> American Journal of Kidney Disease. 30, 459-465 (1997).</li><li>Goyfman, M., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Search&doptcmdl=Citation&defaultField=Title+Word&term=Combined+aquaretic+and+diuretic+therapy+in+acute+heart+failure.">Combined aquaretic and diuretic therapy in acute heart failure.</a> International Journal of Nephrology and Renovascular Disease. 10, 129-134 (2017).</li></ol>

著者が明らかに何もありません。

多くの研究は、ベッドサイド米国であるショック ・呼吸困難5など様々 な病気の状態の管理をガイドとして使用することができます信頼性の高い診断ツールを示しています。優れた感度と特異性肺浮腫の評価であり、B ラインの血管外肺水分量との相関研究米国それ肺肺血管外水2,もささやかな変化を検知できます示されている10. ...

体液貯留が死亡の最も一般的な変更可能な危険因子と心血管イベント ボリューム患者1のオーバー ロードされました。体液貯留は、コントロール不良の高血圧症、心機能低下、肺水腫につながる、この人口の超過死亡率に関連付けられています。患者の症状、血圧や体重の変化を組み合わせることによって患者のボリューム状態の臨床評価は、不正確さ2に傾向がある臨床評価を表しています。この記事は、ベッドサイド超音波 (US) 肺水腫の効果的な管理を導くためのテクニックを利用したプロトコルを提案します。胸と下大静脈 (IVC) 米国は、この水分除去のための提案された臨床プロトコルの基礎を形成します。胸と下大静脈米国循環ショック、末期腎臓病 (ESRD)、急性呼吸不全の管理を含むアプリケーションのスペクトルのための文献で長い実績があります。
胸米国腎不全患者における肺浮腫の評価の客観的なデータを提供するために示されているし、透析が3になると、肺浮腫の減少の重症度を正確に反映します。同様に、下大静脈 (IVC) の米国は長い臨床用途に利用されています。米国は下大静脈は経胸壁心エコー検査のルーチン コンポーネントとしてお勧めし、ボリュームのステータスと4心前負荷のマークは、右心房の圧 (RAP) の推定を含むいくつかの目的を提供しています。いくつかの研究は、下大静脈口径とショック状態5,6流体感度の相関を解明しました。またショック状態の管理に注目、胸部超音波に使用されている米国のベッドサイド アプリケーションによって流体管理制限と呼ばれる方法で一般の循環ショックで輸液蘇生中に新しい肺浮腫の発症を検出肺超音波 (滝) プロトコル7,8。胸と下大静脈超音波肺浮腫の安全かつ効果的な管理のためのよくとり上げられる機能を組み合わせた逆滝プロトコルの名前、プロトコルは、ここで提案します。
ポータブル、またはベッドサイド、米国は放射線への暴露を削減され、患者の搬送が不要とリソース使用率を迅速かつ信頼性の高いデータを提供するイメージ投射様相です。その可用性と関連付けられた副作用の本質的な不在のため監視し、利尿剤治療を調整する米国のベッドサイドを繰り返すことができます。最後に、ベッドサイドは米国、簡単に実行し、リアルタイム9で解釈する臨床医。
米国の胸は、様々 な胸膜および実質の病理を表す特定のアーティファクト パターンを検出し広く受け入れられている手法です。例えば、「A ライン」は胸膜表面の水平方向のエコー (明るい) 残響アーティファクト流体の無料通常実質を示します。また、「B ライン」には胸膜線の下面から始まり、画面の端に拡張無エコー垂直成果物呼吸同期的に移動。疑いのあるボリューム オーバー ロードの設定で B ラインの存在は、血管外肺水分量を示します。これらの B ラインは特質上乾燥ライン アイテム パターン3の再出現につながる、ボリューム削除に対応する方法の中に放散します。研究は、これらの米国の調査結果が密接に関連付けられて上昇肺充填圧力10侵襲的方法により評価したことを示します。
米国は、IVC 容器直径と虚脱、ですがインデックスで自発呼吸の中に直径の減少の割合を測定する使用可能性があります。いくつかの研究は、利尿、肺水腫11症例に対する可能性とこのツールの有効性を示す時 IVC 計測と体積変化の関係を示しています。
ここでは、サンプル米国プロトコル、肺、下大静脈を肺浮腫症における水分除去療法を導き統合逆滝プロトコルを提案する.

<table><tbody><tr><td>Portable Ultrasound machine&amp;nbsp;</td><td>Shown in video: FUGIFILM/Sonosite</td><td>Shown in video:&amp;nbsp; M- Turbo</td><td>Any portable ultrasound machine with the following capabilities&lt;br/&gt; &amp;bull;&amp;nbsp; B- Mode&lt;br/&gt; &amp;bull;&amp;nbsp; M- Mode&lt;br/&gt; &amp;bull;&amp;nbsp; Caliper measurement tool</td></tr><tr><td>Transducer</td><td>Shown in video: FUGIFILM/Sonosite</td><td>Shown in video:&amp;nbsp; P21</td><td>Any ultrasound transducer probe with the following capabilities:&lt;br/&gt; &amp;bull;&amp;nbsp; Phased Array&lt;br/&gt; &amp;bull;&amp;nbsp; Low frequency (1-5MHz)</td></tr></tbody></table>

bedside ultrasound for guiding fluid removal in patients with pulmonary edema: the reverse-falls protocol

体液貯留が死亡と病気のボリューム オーバー ロード状態患者における心血管合併症の最も一般的な危険因子です。利尿や水分除去の程度は、頻繁不正確に応じてある身体検査によって決まります。
ベッドサイド超音波 (米国) は、患者さんのベッドサイドにリアルタイム診断をもたらすポータブル ツールです。この多彩な療法により、患者の血管外と血管内ボリュームの状態を調査する臨床医。肺浮腫の場合は特に、管外のボリュームは、左前胸部の私達によって定量的評価できます。血管内ボリュームを推定するには、下大静脈 (IVC) 口径を可視化.一緒に取られて、肺血管外水分と下大静脈口径程度の利尿効果はまだ安全性肺水腫の治療に必要なレベルを決定する臨床医を導くことができる客観的なデータを提供します。
この記事の目的は三重: 導き、流体管理、2) 3) テクニックを明らかにするガイド流体管理を支援するプロトコルの提案された超音波を記述するためのポータブル性 1) 前回の調査結果を要約するための研究を私たちポータブルを使用して血管内および血管外のボリュームの測定に対応します。

肺超音波は、図 1に示すように a ラインの可視化や B ライン人工物で管外区画中の流体の量を推定します。肺超音波 B 線の量は、図 2に示すように必要な水分の除去量を決定します。混合 a ラインと B ラインのパターン、またはラインの優勢なパターン余分な水分から比較的自由である肺実質を示唆しています。穏やかな利...

Watch this Scientific Journal Video about Bedside Ultrasound for Guiding Fluid Removal in Patients with Pulmonary Edema: The Reverse-FALLS Protocol at JoVE.com

Bedside Ultrasound for Guiding Fluid Removal in Patients with Pulmonary Edema: The Reverse-FALLS Protocol

肺水腫患者指導の水分除去のためのベッドサイド超音波: 逆滝プロトコル

視覚化する臨床医を可能にするイメージング プロトコルについて述べるリアルタイム、患者の血管内および血管外空間のボリュームとそれに応じて利尿および流体の除去パラメーターを設定肺水腫の安全で効率的な治療のため。

Fluid retention is the most common risk factor for mortality and cardiovascular complications in patients with volume-overloaded disease states. The ...

bedside-ultrasound-for-guiding-fluid-removal-patients-with-pulmonary

Research

JoVE Journal

Medicine

11.1K ビュー.  Stony Brook University School of Medicine. 視覚化する臨床医を可能にするイメージング プロトコルについて述べるリアルタイム、患者の血管内および血管外空間のボリュームとそれに応じて利尿および流体の除去パラメーターを設定肺水腫の安全で効率的な治療のため。

ビデオ: Bedside Ultrasound for Guiding Fluid Removal in Patients with Pulmonary Edema: The Reverse-FALLS Protocol

Real-time X-ray Imaging of Lung Fluid Volumes in Neonatal Mouse Lung

At birth, the lung undergoes a profound phenotypic switch from secretion to absorption, which allows for adaptation to breathing independently. Promoting and sustaining this phenotype is critically important in normal alveolar growth and gas exchange throughout life. Several in vitro studies have characterized the role of key regulatory proteins, signaling molecules, and steroid hormones that can influence the rate of lung fluid clearance. However, in vivo examinations must be performed to evaluate whether these regulatory factors play important physiological roles in regulating perinatal lung liquid absorption. As such, the utilization of real time X-ray imaging to determine perinatal lung fluid clearance, or pulmonary edema, represents a technological advancement in the field. Herein, we explain and illustrate an approach to assess the rate of alveolar lung fluid clearance and alveolar flooding in C57BL/6 mice at post natal day 10 using X-ray imaging and analysis. Successful implementation of this protocol requires prior approval from institutional animal care and use committees (IACUC), an in vivo small animal X-ray imaging system, and compatible molecular imaging software.

We present a protocol to assess the rate of alveolar fluid clearance or pulmonary edema in neonatal mouse lung using X-ray imaging technology.

新生児マウスの肺における肺流体体積のリアルタイムX線イメージング

At birth, the lung undergoes a profound phenotypic switch from secretion to absorption, which allows for adaptation to breathing independently. Promoting ...

医学

Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus

Ultrasound is a safe bedside imaging tool that obviates the use of ionizing radiation diagnostic procedures. Due to its convenience, the lung ultrasound has received increasing attention from neonatal physicians. Nevertheless, clear reference standards and guideline limits are needed for accurate application of this diagnostic modality. This document aims to summarize expert opinions and to provide precise guidance to help facilitate the use of the lung ultrasound in the diagnosis of neonatal lung diseases.

Lung ultrasound is a noninvasive and valuable tool for bedside evaluation of neonatal lung diseases. However, a relative lack of reference standards, protocols and guidelines may limit its application. Here, we aim to develop a standardized neonatal lung ultrasound diagnostic protocol to be used in clinical decision-making.

プロトコルおよび国際専門家のコンセンサスに基づいた新生児の肺疾患の診断にポイント ・ オブ ・ ケア肺超音波のためのガイドライン

Ultrasound is a safe bedside imaging tool that obviates the use of ionizing radiation diagnostic procedures. Due to its convenience, the lung ultrasound ...

Ultrasonographic Assessment During Cardiopulmonary Resuscitation

The US-CAB (Ultrasound, Circulation/Airway/Breathing) protocol integrates several sonographic techniques into a structured assessment of the circulation, airway, and breathing status of a patient during cardiopulmonary resuscitation (CPR) in an advanced life support-compliant manner. US-C provides a subxiphoid view of the heart, to look for potentially reversible causes of disease, such as pericardial effusion, pulmonary embolism, hypovolemia, and acute coronary thrombosis. Sonographic cardiac activity during CPR not only helps differentiate pseudo-pulseless electrical activity (PEA) from true PEA but also represents a higher chance of the return of spontaneous circulation (ROSC) and survival. Evaluation of the inferior vena cava (IVC) shows the fluid status of the patient and indicates the best methods to use for fluid resuscitation. If aortic dissection is suspected, a subxiphoid view of the aorta is suggested for identifying an intimal flap. Once intubation is done, tracheal ultrasound (US-A) at the suprasternal notch helps differentiate endotracheal intubation (one air-mucosal interface with one comet-tail) from esophageal intubation (double tract sign). Immediately following US-A, bilateral lung US (US-B) should be done to confirm proper bilateral ventilation using the lung sliding sign. In addition, US-C can be serially followed to see the dynamic changes in the cardiac chambers and IVC, or any cardiac contraction suggestive of ROSC. US-B can also detect coexisting lung or pleural pathologies without interfering with the performance of CPR. The main concern when implementing this method is maintaining high-quality CPR without delays in chest compressions when performing US-CAB. Rigorous training and continued practice are key to minimize any interruptions during resuscitation.

Here, we present a US-CAB (Ultrasound, Circulation/Airway/Breathing) protocol for use during cardiopulmonary resuscitation (CPR). US-C evaluates the subxiphoid view of the heart and inferior vena cava. After intubation, tracheal US (US-A) and lung US (US-B) help confirm endotracheal intubation and proper ventilation.

心肺蘇生中の超音波検査

The US-CAB (Ultrasound, Circulation/Airway/Breathing) protocol integrates several sonographic techniques into a structured assessment of the circulation, ...

Halogenated Agent Delivery in Porcine Model of Acute Respiratory Distress Syndrome via an Intensive Care Unit Type Device

Acute respiratory distress syndrome (ARDS) is a common cause of hypoxemic respiratory failure and death in critically ill patients, and there is an urgent need to find effective therapies. Preclinical studies have shown that inhaled halogenated agents may have beneficial effects in animal models of ARDS. The development of new devices to administer halogenated agents using modern intensive care unit (ICU) ventilators has significantly simplified the dispensing of halogenated agents to ICU patients. Because previous experimental and clinical research suggested potential benefits of halogenated volatiles, such as sevoflurane or isoflurane, for lung alveolar epithelial injury and inflammation, two pathophysiologic landmarks of diffuse alveolar damage during ARDS, we designed an animal model to understand the mechanisms of the effects of halogenated agents on lung injury and repair. After general anesthesia, tracheal intubation, and the initiation of mechanical ventilation, ARDS was induced in piglets via the intratracheal instillation of hydrochloric acid. Then, the piglets were sedated with inhaled sevoflurane or isoflurane using an ICU-type device, and the animals were ventilated with lung-protective mechanical ventilation during a 4 h period. During the study period, blood and alveolar samples were collected to evaluate arterial oxygenation, the permeability of the alveolar-capillary membrane, alveolar fluid clearance, and lung inflammation. Mechanical ventilation parameters were also collected throughout the experiment. Although this model induced a marked decrease in arterial oxygenation with altered alveolar-capillary permeability, it is reproducible and is characterized by a rapid onset, good stability over time, and no fatal complications.
We have developed a piglet model of acid aspiration that reproduces most of the physiological, biological, and pathological features of clinical ARDS, and it will be helpful to further our understanding of the potential lung-protective effects of halogenated agents delivered through devices used for inhaled ICU sedation.

We describe a model of hydrochloric acid-induced acute respiratory distress syndrome (ARDS) in piglets receiving sedation with halogenated agents, isoflurane and sevoflurane, through a device used for inhaled intensive care sedation. This model can be used to investigate the biological mechanisms of halogenated agents on lung injury and repair.

集中治療室型装置による急性呼吸窮迫症候群の豚モデルにおけるハロゲン化剤の送達

Acute respiratory distress syndrome (ARDS) is a common cause of hypoxemic respiratory failure and death in critically ill patients, and there is an urgent ...

Continuous Venous-Arterial Doppler Ultrasound During a Preload Challenge

A preload challenge (PC) is a clinical maneuver that, first, increases the cardiac filling (i.e., preload) and, second, calculates the change in cardiac output. Fundamentally, a PC is a bedside approach for testing the Frank-Starling-Sarnoff (i.e., "cardiac function") curve. Normally, this curve has a steep slope such that a small change in the cardiac preload generates a large change in the stroke volume (SV) or cardiac output. However, in various disease states, the slope of this relationship flattens such that increasing the volume into the heart leads to little rise in the SV. In this pathological scenario, additional cardiac preload (e.g., intravenous fluid) is unlikely to be physiologically effective and could lead to harm if organ congestion evolves. Therefore, inferring both the cardiac preload and output is clinically useful as it may guide intravenous (IV) fluid resuscitation. Accordingly, the goal of this protocol is to describe a method for contemporaneously tracking the surrogates of cardiac preload and output using a novel, wireless, wearable ultrasound during a well-validated preload challenge.

The Frank-Starling-Sarnoff curve is clinically important and describes the relationship between cardiac preload and output. This report illustrates a novel method of simultaneous jugular venous and carotid arterial Doppler velocimetry as transient surrogates of cardiac preload and output, respectively; this approach is enabled by wireless, wearable Doppler ultrasound.

プリロードチャレンジ中の連続静脈動脈ドップラー超音波

A preload challenge (PC) is a clinical maneuver that, first, increases the cardiac filling (i.e., preload) and, second, calculates the change in cardiac ...

Image Acquisition Method for the Sonographic Assessment of the Inferior Vena Cava

Over the past several decades, clinicians have incorporated several applications of diagnostic point-of-care ultrasound (POCUS) into medical decision-making. Among the applications of POCUS, imaging the inferior vena cava (IVC) is practiced by a wide variety of specialties, such as nephrology, emergency medicine, internal medicine, critical care, anesthesiology, pulmonology, and cardiology. Although each specialty uses IVC data in slightly different ways, most medical specialties, at minimum, attempt to use IVC data to make predictions about intravascular volume status. While the relationship between IVC sonographic data and intravascular volume status is complex and highly context-dependent, all clinicians should collect the sonographic data in standardized ways to ensure repeatability. This paper describes standardized IVC image acquisition including patient positioning, transducer selection, probe placement, image optimization, and the pitfalls and limitations of IVC sonographic imaging.&#160;This paper also describes the commonly performed anterior IVC long-axis view and three other views of the IVC that can each provide helpful diagnostic information when the anterior long-axis view is difficult to obtain or interpret.

Point-of-care ultrasound evaluation of the inferior vena cava (IVC) is commonly utilized to identify, among other things, the volume status. Imaging should be performed systematically to ensure repeatability. This manuscript reviews the methods and pitfalls of sonographic IVC examination.

下大静脈の超音波評価のための画像取得方法

Over the past several decades, clinicians have incorporated several applications of diagnostic point-of-care ultrasound (POCUS) into medical ...

Point-of-Care Lung Ultrasound in Adults: Image Acquisition

Consultative ultrasound performed by radiologists has traditionally not been used for imaging the lungs, as the lungs&#39; air-filled nature normally prevents direct visualization of the lung parenchyma. When showing the lung parenchyma, ultrasound typically generates a number of non-anatomic artifacts. However, over the past several decades, these artifacts have been studied by diagnostic point-of-care ultrasound (POCUS) practitioners, who have identified findings that have value in narrowing the differential diagnoses of cardiopulmonary dysfunction. For instance, in patients presenting with dyspnea, lung POCUS is superior to chest radiography (CXR) for the diagnosis of pneumothorax, pulmonary edema, lung consolidations, and pleural effusions. Despite its known diagnostic value, the utilization of lung POCUS in clinical medicine remains variable, in part because training in this modality across hospitals remains inconsistent. To address this educational gap, this narrative review describes lung POCUS image acquisition in adults, including patient positioning, transducer selection, probe placement, acquisition sequence, and image optimization.

Point-of-care ultrasound (POCUS) of the lungs provides quick answers in rapidly changing clinical scenarios. We present an efficient and informative protocol for image acquisition for use in acute care settings.

成人におけるポイントオブケア肺超音波:画像取得

Consultative ultrasound performed by radiologists has traditionally not been used for imaging the lungs, as the lungs&#39; air-filled nature normally ...

A Modified Sonographic Algorithm for Image Acquisition in Life-Threatening Emergencies in the Critically Ill Newborn

The use of routine point-of-care ultrasound (POCUS) is increasing in neonatal intensive care units (NICUs), with several centers advocating for 24 h equipment availability. In 2018, the sonographic algorithm for life-threatening emergencies (SAFE) protocol was published, which allows the assessment of neonates with sudden decompensation to identify abnormal contractility, tamponade, pneumothorax, and pleural effusion. In the study unit (with a consulting neonatal hemodynamics and POCUS service), the algorithm was adapted by including consolidated core steps to support at-risk newborns, aiding clinicians in managing cardiac arrest, and adding views to verify correct intubation. This paper presents a protocol that can be applied in the NICU and the delivery room (DR) in relation to three scenarios: cardiac arrest, hemodynamic deterioration, or respiratory decompensation. 
This protocol can be performed with a state-of-the-art ultrasound machine or an affordable handheld device; the image acquisition protocol is carefully detailed. This method was designed to be learned as a general competence to obtain the timely diagnosis of life-threatening scenarios; the method aims to save time but does not represent a substitute for comprehensive and standardized hemodynamic and radiological analyses by a multidisciplinary team, which might not universally be on call but needs to be involved in the process. From January 2019 to July 2022, in our center, 1,045 hemodynamic consultation/POCUS consults were performed with 25 patients requiring the modified SAFE protocol (2.3%), and a total of 19 procedures were performed. In five cases, trained fellows on call resolved life-threatening situations. Clinical examples are provided that show the importance of including this technique in the care of critical newborns.

Here, we present a protocol that can be applied in the neonatal intensive care unit and the delivery room in relation to three scenarios: cardiac arrest, hemodynamic deterioration, or respiratory decompensation. This protocol can be performed with a state-of-the-art ultrasound machine or an affordable handheld device; an image acquisition protocol is carefully detailed.

重症新生児の生命を脅かす緊急事態における画像取得のための修正超音波アルゴリズム

The use of routine point-of-care ultrasound (POCUS) is increasing in neonatal intensive care units (NICUs), with several centers advocating for 24 h ...

<meta charset="utf8"></head><body>心不全の管理におけるIVC評価のためのPOCUSプロトコル

Workflow and Framework for Collecting and Implementing Point-of-Care Ultrasound Data in the Management of Heart Failure Patients

Management and prevention of acute decompensated heart failure remain highly prevalent and challenging medical conditions. Incorporation of Point-of-Care Ultrasound (POCUS) as an adjunctive tool for assessing volume status and treatment response has shown significant promise. POCUS can be used for imaging internal anatomic structures serially and capturing these images for comparison and measurement over time. This protocol describes a scalable and standardized methodology for the serial assessment of the inferior vena cava (IVC). The methodology includes serial image collection, measurement, and presentation in the electronic medical record. A workflow for POCUS-acquired images of the IVC was created to capture the images and measure the diameter in a discrete data field for direct comparison over time and in response to clinical management. The protocol also includes the assessment of the presence or absence of pleural effusion as discrete data in the standardized workflow. By integrating POCUS into heart failure management, clinicians can improve patient outcomes through more precise and timely adjustments in treatment.

<meta charset="utf8"></head><body>著者スポットライト:心不全患者を管理するためのPOCUSデータをEHRに統合するためのワークフロー

This protocol presents a scalable workflow for the use of point-of-care ultrasound in the management of hospitalized and outpatient heart failure patients.

心不全患者の管理におけるポイントオブケア超音波データの収集と実装のためのワークフローとフレームワーク 

Management and prevention of acute decompensated heart failure remain highly prevalent and challenging medical conditions. Incorporation of Point-of-Care ...

肺水腫患者指導の水分除去のためのベッドサイド超音波: 逆滝プロトコル

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この動画の章

新生児マウスの肺における肺流体体積のリアルタイムX線イメージング

プロトコルおよび国際専門家のコンセンサスに基づいた新生児の肺疾患の診断にポイント・オブ・ケア肺超音波のためのガイドライン

心肺蘇生中の超音波検査

集中治療室型装置による急性呼吸窮迫症候群の豚モデルにおけるハロゲン化剤の送達

プリロードチャレンジ中の連続静脈動脈ドップラー超音波

下大静脈の超音波評価のための画像取得方法

成人におけるポイントオブケア肺超音波:画像取得

重症新生児の生命を脅かす緊急事態における画像取得のための修正超音波アルゴリズム

心不全患者の管理におけるポイントオブケア超音波データの収集と実装のためのワークフローとフレームワーク

心不全患者の管理におけるポイントオブケア超音波データの収集と実装のためのワークフローとフレームワーク

肺水腫患者指導の水分除去のためのベッドサイド超音波: 逆滝プロトコル

要約

さらに動画を探す

この動画の章

新生児マウスの肺における肺流体体積のリアルタイムX線イメージング

プロトコルおよび国際専門家のコンセンサスに基づいた新生児の肺疾患の診断にポイント ・ オブ ・ ケア肺超音波のためのガイドライン

心肺蘇生中の超音波検査

集中治療室型装置による急性呼吸窮迫症候群の豚モデルにおけるハロゲン化剤の送達

プリロードチャレンジ中の連続静脈動脈ドップラー超音波

下大静脈の超音波評価のための画像取得方法

成人におけるポイントオブケア肺超音波:画像取得

重症新生児の生命を脅かす緊急事態における画像取得のための修正超音波アルゴリズム

心不全患者の管理におけるポイントオブケア超音波データの収集と実装のためのワークフローとフレームワーク

心不全患者の管理におけるポイントオブケア超音波データの収集と実装のためのワークフローとフレームワーク

プロトコルおよび国際専門家のコンセンサスに基づいた新生児の肺疾患の診断にポイント・オブ・ケア肺超音波のためのガイドライン