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Semi-Quantitative Determination of Dopaminergic Neuron Density in the Substantia Nigra of Rodent Models using Automated Image Analysis

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06:09 min

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February 2nd, 2021

DOI :

10.3791/62062-v

February 2nd, 2021

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4,282 Views

Darren M. O'Hara¹^,², Minesh Kapadia¹^,², Susan Ping¹^,², Suneil K. Kalia¹^,²^,³, Lorraine V. Kalia¹^,²^,⁴^,⁵^,⁶

¹Krembil Research Institute, Toronto Western Hospital, University Health Network, ²Department of Laboratory Medicine and Pathobiology, University of Toronto, ³Department of Surgery, Division of Neurosurgery, University of Toronto, ⁴Department of Medicine, Division of Neurology, University of Toronto, ⁵Department of Medicine, Division of Neurology, Edmond J. Safra Program in Parkinson's Disease and the Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, University Health Network, ⁶Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto

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Dopaminergic Neuron Density

Substantia Nigra

Rodent Models

Automated Image Analysis

Parkinson s Disease Research

Image Analysis Software

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