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Conditional calcineurin knockout mice exhibit multiple abnormal behaviors related to schizophrenia.
Proceedings of the National Academy of Sciences of the United States of America Jul, 2003 | Pubmed ID: 12851457
Evidence for association of schizophrenia with genetic variation in the 8p21.3 gene, PPP3CC, encoding the calcineurin gamma subunit.
Proceedings of the National Academy of Sciences of the United States of America Jul, 2003 | Pubmed ID: 12851458
Acceleration of visually cued conditioned fear through the auditory pathway.
Nature neuroscience Sep, 2004 | Pubmed ID: 15322551
M2 毒蕈碱样乙酰胆碱受体敲除小鼠显示行为的灵活性、 工作记忆和海马可塑性的赤字。
The Journal of neuroscience : the official journal of the Society for Neuroscience Nov, 2004 | Pubmed ID: 15537882
Enhanced cocaine responsiveness and impaired motor coordination in metabotropic glutamate receptor subtype 2 knockout mice.
Proceedings of the National Academy of Sciences of the United States of America Mar, 2005 | Pubmed ID: 15753323
Tight junctions in Schwann cells of peripheral myelinated axons: a lesson from claudin-19-deficient mice.
The Journal of cell biology May, 2005 | Pubmed ID: 15883201
[Stress and animal model of psychiatric disease].
Nihon yakurigaku zasshi. Folia pharmacologica Japonica Sep, 2005 | Pubmed ID: 16272762
NFAT dysregulation by increased dosage of DSCR1 and DYRK1A on chromosome 21.
Nature Jun, 2006 | Pubmed ID: 16554754
Schizophrenia-relevant behavioral testing in rodent models: a uniquely human disorder?
Biological psychiatry Jun, 2006 | Pubmed ID: 16797265
Investigating gene-to-behavior pathways in psychiatric disorders: the use of a comprehensive behavioral test battery on genetically engineered mice.
Annals of the New York Academy of Sciences Nov, 2006 | Pubmed ID: 17185513
Sept4, a component of presynaptic scaffold and Lewy bodies, is required for the suppression of alpha-synuclein neurotoxicity.
Neuron Feb, 2007 | Pubmed ID: 17296554
Mouse liaison for integrative brain research.
Neuroscience research Jun, 2007 | Pubmed ID: 17382419
Enriched environments influence depression-related behavior in adult mice and the survival of newborn cells in their hippocampi.
Behavioural brain research Jun, 2007 | Pubmed ID: 17397941
Impact of brain-behavior phenotypying of genetically-engineered mice on research of neuropsychiatric disorders.
Neuroscience research Jun, 2007 | Pubmed ID: 17524507
Selective impairment of working memory in a mouse model of chronic cerebral hypoperfusion.
Stroke; a journal of cerebral circulation Oct, 2007 | Pubmed ID: 17761909
Altered sensitivities to morphine and cocaine in scaffold protein tamalin knockout mice.
Proceedings of the National Academy of Sciences of the United States of America Sep, 2007 | Pubmed ID: 17766434
Genetic ablation of NMDA receptor subunit NR3B in mouse reveals motoneuronal and nonmotoneuronal phenotypes.
The European journal of neuroscience Sep, 2007 | Pubmed ID: 17880385
Increased social interaction in mice deficient of the striatal medium spiny neuron-specific phosphodiesterase 10A2.
Journal of neurochemistry Apr, 2008 | Pubmed ID: 18088367
Smaller dendritic spines, weaker synaptic transmission, but enhanced spatial learning in mice lacking Shank1.
The Journal of neuroscience : the official journal of the Society for Neuroscience Feb, 2008 | Pubmed ID: 18272690
Increased anxiety-like behavior in neuropsin (kallikrein-related peptidase 8) gene-deficient mice.
Behavioral neuroscience Jun, 2008 | Pubmed ID: 18513120
[Investigating genes-to-behavior pathways in psychiatric diseases: an approach using a comprehensive behavioral test battery on genetically engineered mice].
Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology Jun, 2008 | Pubmed ID: 18646600
Mice lacking the schizophrenia-associated protein FEZ1 manifest hyperactivity and enhanced responsiveness to psychostimulants.
Human molecular genetics Oct, 2008 | Pubmed ID: 18647754
Identification of YWHAE, a gene encoding 14-3-3epsilon, as a possible susceptibility gene for schizophrenia.
Human molecular genetics Oct, 2008 | Pubmed ID: 18658164
Roles of continuous neurogenesis in the structural and functional integrity of the adult forebrain.
Nature neuroscience Oct, 2008 | Pubmed ID: 18758458
Alpha-CaMKII deficiency causes immature dentate gyrus, a novel candidate endophenotype of psychiatric disorders.
Molecular brain , 2008 | Pubmed ID: 18803808
Comprehensive behavioral phenotyping of calpastatin-knockout mice.
Molecular brain , 2008 | Pubmed ID: 18803809
Impaired long-term memory retention and working memory in sdy mutant mice with a deletion in Dtnbp1, a susceptibility gene for schizophrenia.
Molecular brain , 2008 | Pubmed ID: 18945333
Mice lacking the kf-1 gene exhibit increased anxiety- but not despair-like behavior.
Frontiers in behavioral neuroscience , 2008 | Pubmed ID: 18958194
Down-regulation of protocadherin-alpha A isoforms in mice changes contextual fear conditioning and spatial working memory.
The European journal of neuroscience Oct, 2008 | Pubmed ID: 18973563
Normal mitochondrial respiratory function is essential for spatial remote memory in mice.
Molecular brain , 2008 | Pubmed ID: 19087269
Comprehensive behavioral phenotyping of ryanodine receptor type 3 (RyR3) knockout mice: decreased social contact duration in two social interaction tests.
Frontiers in behavioral neuroscience , 2009 | Pubmed ID: 19503748
Abnormal social behavior, hyperactivity, impaired remote spatial memory, and increased D1-mediated dopaminergic signaling in neuronal nitric oxide synthase knockout mice.
Molecular brain , 2009 | Pubmed ID: 19538708
Abnormal behavior in a chromosome-engineered mouse model for human 15q11-13 duplication seen in autism.
Cell Jun, 2009 | Pubmed ID: 19563756
Mice with altered myelin proteolipid protein gene expression display cognitive deficits accompanied by abnormal neuron-glia interactions and decreased conduction velocities.
The Journal of neuroscience : the official journal of the Society for Neuroscience Jul, 2009 | Pubmed ID: 19571127
Intrauterine environment-genome interaction and children's development (4): Brain-behavior phenotypying of genetically-engineered mice using a comprehensive behavioral test battery on research of neuropsychiatric disorders.
The Journal of toxicological sciences , 2009 | Pubmed ID: 19571483
Inhibition of calpain increases LIS1 expression and partially rescues in vivo phenotypes in a mouse model of lissencephaly.
Nature medicine Oct, 2009 | Pubmed ID: 19734909
Neural activity changes underlying the working memory deficit in alpha-CaMKII heterozygous knockout mice.
Frontiers in behavioral neuroscience , 2009 | Pubmed ID: 19750198
KF-1 Ubiquitin Ligase: An Anxiety Suppressor.
Frontiers in neuroscience May, 2009 | Pubmed ID: 19753093
Abnormalities in brain structure and behavior in GSK-3alpha mutant mice.
Molecular brain , 2009 | Pubmed ID: 19925672
Nardilysin regulates axonal maturation and myelination in the central and peripheral nervous system.
Nature neuroscience Dec, 2009 | Pubmed ID: 19935654
Ischemia-induced neurogenesis of neocortical layer 1 progenitor cells.
Nature neuroscience Feb, 2010 | Pubmed ID: 20037576
SDOP-DB: a comparative standardized-protocol database for mouse phenotypic analyses.
Bioinformatics (Oxford, England) Apr, 2010 | Pubmed ID: 20194625
Comprehensive behavioral analysis of calcium/calmodulin-dependent protein kinase IV knockout mice.
PloS one , 2010 | Pubmed ID: 20209163
Reversal of hippocampal neuronal maturation by serotonergic antidepressants.
Proceedings of the National Academy of Sciences of the United States of America May, 2010 | Pubmed ID: 20404165
A mouse model characterizing features of vascular dementia with hippocampal atrophy.
Stroke; a journal of cerebral circulation Jun, 2010 | Pubmed ID: 20448204
Case reports: Painful limbs/moving extremities: report of two cases.
Clinical orthopaedics and related research Dec, 2010 | Pubmed ID: 20585912
[Immature dentate gyrus as a candidate endophenotype of psychiatric disorders].
Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology Jun, 2010 | Pubmed ID: 20666142
Behavioral profiles of three C57BL/6 substrains.
Frontiers in behavioral neuroscience , 2010 | Pubmed ID: 20676234
Stress-evoked tyrosine phosphorylation of signal regulatory protein α regulates behavioral immobility in the forced swim test.
The Journal of neuroscience : the official journal of the Society for Neuroscience Aug, 2010 | Pubmed ID: 20685990
Expression of tryptophan 2,3-dioxygenase in mature granule cells of the adult mouse dentate gyrus.
Molecular brain , 2010 | Pubmed ID: 20815922
Inactivation of fibroblast growth factor binding protein 3 causes anxiety-related behaviors.
Molecular and cellular neurosciences Jan, 2011 | Pubmed ID: 20851768
Right-hemispheric dominance of spatial memory in split-brain mice.
Hippocampus Feb, 2012 | Pubmed ID: 21069782
[Genes, behaviors and psychiatric disorders].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme Mar, 2008 | Pubmed ID: 21089339
Decreased exploratory activity in a mouse model of 15q duplication syndrome; implications for disturbance of serotonin signaling.
PloS one , 2010 | Pubmed ID: 21179543
The influence of chronic cerebral hypoperfusion on cognitive function and amyloid β metabolism in APP overexpressing mice.
PloS one , 2011 | Pubmed ID: 21305033
Chronic treatment with fluoxetine for more than 6 weeks decreases neurogenesis in the subventricular zone of adult mice.
Molecular brain , 2011 | Pubmed ID: 21385396
Synaptic E3 ligase SCRAPPER in contextual fear conditioning: extensive behavioral phenotyping of Scrapper heterozygote and overexpressing mutant mice.
PloS one , 2011 | Pubmed ID: 21390313
Forebrain-specific constitutively active CaMKKα transgenic mice show deficits in hippocampus-dependent long-term memory.
Neurobiology of learning and memory Sep, 2011 | Pubmed ID: 21558011
P301S mutant human tau transgenic mice manifest early symptoms of human tauopathies with dementia and altered sensorimotor gating.
PloS one , 2011 | Pubmed ID: 21698260
Relaxin-3-deficient mice showed slight alteration in anxiety-related behavior.
Frontiers in behavioral neuroscience , 2011 | Pubmed ID: 21887138
Expression of the AMPA Receptor Subunits GluR1 and GluR2 is Associated with Granule Cell Maturation in the Dentate Gyrus.
Frontiers in neuroscience , 2011 | Pubmed ID: 21927594
DIP/WISH deficiency enhances synaptic function and performance in the Barnes maze.
Molecular brain , 2011 | Pubmed ID: 22018352
Adenomatous polyposis coli heterozygous knockout mice display hypoactivity and age-dependent working memory deficits.
Frontiers in behavioral neuroscience , 2011 | Pubmed ID: 22347851
Comprehensive behavioral analysis of ENU-induced Disc1-Q31L and -L100P mutant mice.
BMC research notes Feb, 2012 | Pubmed ID: 22348257
M4 muscarinic receptor knockout mice display abnormal social behavior and decreased prepulse inhibition.
Molecular brain , 2012 | Pubmed ID: 22463818
α-Synuclein BAC transgenic mice as a model for Parkinson's disease manifested decreased anxiety-like behavior and hyperlocomotion.
Neuroscience research Jun, 2012 | Pubmed ID: 22475625
Increased astrocytic ATP release results in enhanced excitability of the hippocampus.
Glia Feb, 2013 | Pubmed ID: 23018918
Comprehensive behavioral analysis of pituitary adenylate cyclase-activating polypeptide (PACAP) knockout mice.
Frontiers in behavioral neuroscience , 2012 | Pubmed ID: 23060763
Impaired synaptic clustering of postsynaptic density proteins and altered signal transmission in hippocampal neurons, and disrupted learning behavior in PDZ1 and PDZ2 ligand binding-deficient PSD-95 knockin mice.
Molecular brain , 2012 | Pubmed ID: 23268962
Behavioral abnormalities observed in Zfhx2-deficient mice.
PloS one , 2012 | Pubmed ID: 23300874
Fluoxetine-induced cortical adult neurogenesis.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology May, 2013 | Pubmed ID: 23303069
Deficiency of schnurri-2, an MHC enhancer binding protein, induces mild chronic inflammation in the brain and confers molecular, neuronal, and behavioral phenotypes related to schizophrenia.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology Jul, 2013 | Pubmed ID: 23389689
Post-natal treatment by a blood-brain-barrier permeable calpain inhibitor, SNJ1945 rescued defective function in lissencephaly.
Scientific reports , 2013 | Pubmed ID: 23390575
Synaptosomal-associated protein 25 mutation induces immaturity of the dentate granule cells of adult mice.
Molecular brain , 2013 | Pubmed ID: 23497716
The immature dentate gyrus represents a shared phenotype of mouse models of epilepsy and psychiatric disease.
Bipolar disorders Jun, 2013 | Pubmed ID: 23560889
ENU-mutagenesis mice with a non-synonymous mutation in Grin1 exhibit abnormal anxiety-like behaviors, impaired fear memory, and decreased acoustic startle response.
BMC research notes , 2013 | Pubmed ID: 23688147
Immature dentate gyrus: an endophenotype of neuropsychiatric disorders.
Neural plasticity , 2013 | Pubmed ID: 23840971
Chronic overload of SEPT4, a parkin substrate that aggregates in Parkinson's disease, causes behavioral alterations but not neurodegeneration in mice.
Molecular brain , 2013 | Pubmed ID: 23938054
Orexin receptor-1 in the locus coeruleus plays an important role in cue-dependent fear memory consolidation.
The Journal of neuroscience : the official journal of the Society for Neuroscience Sep, 2013 | Pubmed ID: 24005305
Point mutation in syntaxin-1A causes abnormal vesicle recycling, behaviors, and short term plasticity.
The Journal of biological chemistry Nov, 2013 | Pubmed ID: 24136198
Chronic fluoxetine treatment reduces parvalbumin expression and perineuronal nets in gamma-aminobutyric acidergic interneurons of the frontal cortex in adult mice.
Molecular brain , 2013 | Pubmed ID: 24228616
In vivo evaluation of cellular activity in αCaMKII heterozygous knockout mice using manganese-enhanced magnetic resonance imaging (MEMRI).
Frontiers in integrative neuroscience , 2013 | Pubmed ID: 24273499
PRICKLE1 interaction with SYNAPSIN I reveals a role in autism spectrum disorders.
PloS one , 2013 | Pubmed ID: 24312498
Microendoscopy-assisted muscle-preserving interlaminar decompression for lumbar spinal stenosis: clinical results of consecutive 105 cases with more than 3-year follow-up.
Spine Mar, 2014 | Pubmed ID: 24365896
Mice lacking collapsin response mediator protein 1 manifest hyperactivity, impaired learning and memory, and impaired prepulse inhibition.
Frontiers in behavioral neuroscience , 2013 | Pubmed ID: 24409129
Absence of BRINP1 in mice causes increase of hippocampal neurogenesis and behavioral alterations relevant to human psychiatric disorders.
Molecular brain , 2014 | Pubmed ID: 24528488
Increased behavioral and neuronal responses to a hallucinogenic drug in PACAP heterozygous mutant mice.
PloS one , 2014 | Pubmed ID: 24586556
Comprehensive behavioral analysis of cluster of differentiation 47 knockout mice.
PloS one , 2014 | Pubmed ID: 24586890
Targeted deletion of the C-terminus of the mouse adenomatous polyposis coli tumor suppressor results in neurologic phenotypes related to schizophrenia.
Molecular brain , 2014 | Pubmed ID: 24678719
Comprehensive behavioral study of mGluR3 knockout mice: implication in schizophrenia related endophenotypes.
Molecular brain , 2014 | Pubmed ID: 24758191
Hippocampal neurogenesis regulates forgetting during adulthood and infancy.
Science (New York, N.Y.) May, 2014 | Pubmed ID: 24812394
Transcriptomic evidence for immaturity of the prefrontal cortex in patients with schizophrenia.
Molecular brain , 2014 | Pubmed ID: 24886351
Enhanced stability of hippocampal place representation caused by reduced magnesium block of NMDA receptors in the dentate gyrus.
Molecular brain , 2014 | Pubmed ID: 24893573
Mechanisms for interferon-α-induced depression and neural stem cell dysfunction.
Stem cell reports Jul, 2014 | Pubmed ID: 25068123
[Immaturity of brain as an endophenotype of neuropsychiatric disorders].
Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology Jun, 2014 | Pubmed ID: 25076776
Genomic responses in mouse models greatly mimic human inflammatory diseases.
Proceedings of the National Academy of Sciences of the United States of America Jan, 2015 | Pubmed ID: 25092317
SIRT1 overexpression ameliorates a mouse model of SOD1-linked amyotrophic lateral sclerosis via HSF1/HSP70i chaperone system.
Molecular brain , 2014 | Pubmed ID: 25167838
Transient receptor potential ankyrin 1 in spinal cord dorsal horn is involved in neuropathic pain in nerve root constriction rats.
Molecular pain , 2014 | Pubmed ID: 25192906
IL1RAPL1 knockout mice show spine density decrease, learning deficiency, hyperactivity and reduced anxiety-like behaviours.
Scientific reports , 2014 | Pubmed ID: 25312502
Reply to Warren et al. and Shay et al.: Commonalities across species do exist and are potentially important.
Proceedings of the National Academy of Sciences of the United States of America Jan, 2015 | Pubmed ID: 25540421
1, Japan Science and Technology Agency, Core Research for Evolutionary Science and Technology (CREST),
2Division of Systems Medical Science, Institute for Comprehensive Medical Science, Fujita Health University,
3Department of Psychiatry, Graduate School of Medicine, Kyoto University,
4Genetic Engineering and Functional Genomics Group, Horizontal Medical Research Organization, Graduate School of Medicine, Kyoto University,
5Center for Genetic Analysis of Behavior, National Institute for Physiological Sciences, National Institutes of Natural Sciences
1Division of Systems Medical Science, Institute for Comprehensive Medical Science, Fujita Health University,
2, Japan Science and Technology Agency, Core Research for Evolutionary Science and Technology (CREST),
3Center for Genetic Analysis of Behavior, National Institute for Physiological Sciences, National Institutes of Natural Sciences
1Division of Systems Medical Science, Institute for Comprehensive Medical Science, Fujita Health University,
2Japan Science and Technology Agency, Core Research for Evolutionary Science and Technology (CREST),
3Center for Genetic Analysis of Behavior, National Institute for Physiological Sciences, National Institutes of Natural Sciences
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