Center for Engineering in Medicine
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Effects of immobilized glycosaminoglycans on the proliferation and differentiation of mesenchymal stem cells.
Tissue engineering. Part A Nov, 2009 | Pubmed ID: 19456238
High throughput single cell bioinformatics.
Biotechnology progress Nov-Dec, 2009 | Pubmed ID: 19830811
Membrane thickness is an important variable in membrane scaffolds: Influence of chitosan membrane structure on the behavior of cells.
Acta biomaterialia Jun, 2010 | Pubmed ID: 19925888
Cell delivery: from cell transplantation to organ engineering.
Cell transplantation , 2010 | Pubmed ID: 20525441
Retinal pigment epithelium differentiation of stem cells: current status and challenges.
Critical reviews in biomedical engineering , 2009 | Pubmed ID: 20528731
Organ reengineering through development of a transplantable recellularized liver graft using decellularized liver matrix.
Nature medicine Jul, 2010 | Pubmed ID: 20543851
Differentiating stem cells into liver.
Biotechnology & genetic engineering reviews , 2008 | Pubmed ID: 21412354
Application of whole-organ tissue engineering in hepatology.
Nature reviews. Gastroenterology & hepatology Dec, 2012 | Pubmed ID: 22890112
Engineered liver for transplantation.
Current opinion in biotechnology Oct, 2013 | Pubmed ID: 23791465
Supercooling as a viable non-freezing cell preservation method of rat hepatocytes.
PloS one , 2013 | Pubmed ID: 23874947
Supercooling enables long-term transplantation survival following 4 days of liver preservation.
Nature medicine Jul, 2014 | Pubmed ID: 24973919
SIMPLE MACHINE PERFUSION SIGNIFICANTLY ENHANCES HEPATOCYTE YIELDS OF ISCHEMIC AND FRESH RAT LIVERS.
Cell medicine , 2013 | Pubmed ID: 25431743
Tissue heterogeneity in structure and conductivity contribute to cell survival during irreversible electroporation ablation by "electric field sinks".
Scientific reports , 2015 | Pubmed ID: 25684630
Proteomic analysis of naturally-sourced biological scaffolds.
Biomaterials Jan, 2016 | Pubmed ID: 26476196
Rat liver regeneration following ablation with irreversible electroporation.
PeerJ , 2016 | Pubmed ID: 26819842
Nondestructive Methods for Monitoring Cell Removal During Rat Liver Decellularization.
Tissue engineering. Part C, Methods Jul, 2016 | Pubmed ID: 27169332
Functionalized Biopolymer Particles Enhance Performance of a Tissue-Protective Peptide under Proteolytic and Thermal Stress.
Biomacromolecules Jun, 2016 | Pubmed ID: 27219509
Discarded Livers Find a New Life: Engineered Liver Grafts Using Hepatocytes Recovered From Marginal Livers.
Artificial organs Jun, 2017 | Pubmed ID: 27862079
Immune responses to bioengineered organs.
Current opinion in organ transplantation Feb, 2017 | Pubmed ID: 27926545
Co-delivery of a growth factor and a tissue-protective molecule using elastin biopolymers accelerates wound healing in diabetic mice.
Biomaterials Oct, 2017 | Pubmed ID: 28688286
Preparation of Decellularized Liver Scaffolds and Recellularized Liver Grafts.
Methods in molecular biology (Clifton, N.J.) , 2018 | Pubmed ID: 28735385
Decellularized human liver extracellular matrix (hDLM)-mediated hepatic differentiation of human induced pluripotent stem cells (hIPSCs).
Journal of tissue engineering and regenerative medicine Apr, 2018 | Pubmed ID: 29222839
Improving functional re-endothelialization of acellular liver scaffold using REDV cell-binding domain.
Acta biomaterialia Sep, 2018 | Pubmed ID: 30071351
Layer-by-layer heparinization of decellularized liver matrices to reduce thrombogenicity of tissue engineered grafts.
Journal of clinical and translational research Jul, 2015 | Pubmed ID: 30873444
Editorial: On Tissue Engineering and Regenerative Medicine of Skin and Its Appendages.
Frontiers in physiology , 2019 | Pubmed ID: 31244678
Liver Bioengineering: Promise, Pitfalls, and Hurdles to Overcome.
Current transplantation reports Jun, 2019 | Pubmed ID: 31289714
Repopulation of intrahepatic bile ducts in engineered rat liver grafts.
Technology , 2019 | Pubmed ID: 31388515
Tissue scaffolds functionalized with therapeutic elastin-like biopolymer particles.
Biotechnology and bioengineering May, 2020 | Pubmed ID: 31956985
Development of liver microtissues with functional biliary ductular network.
Biotechnology and bioengineering Jan, 2021 | Pubmed ID: 32856740
Liver donor age affects hepatocyte function through age-dependent changes in decellularized liver matrix.
Biomaterials Mar, 2021 | Pubmed ID: 33524812
Engineering Vascularized Composite Allografts Using Natural Scaffolds: A Systematic Review.
Tissue engineering. Part B, Reviews Jun, 2022 | Pubmed ID: 34238047
Combinatorial Use of Therapeutic ELP-Based Micelle Particles in Tissue Engineering.
Advanced healthcare materials Jul, 2022 | Pubmed ID: 35373501
Human-Origin iPSC-Based Recellularization of Decellularized Whole Rat Livers.
Bioengineering (Basel, Switzerland) May, 2022 | Pubmed ID: 35621497
Acellular nipple scaffold development, characterization, and preliminary biocompatibility assessment in a swine model.
Plastic and reconstructive surgery Dec, 2022 | Pubmed ID: 36472499
Regenerative medicine applications: An overview of clinical trials.
Frontiers in bioengineering and biotechnology , 2022 | Pubmed ID: 36507264
Microvascular assessment of fascio-cutaneous flaps by ultrasound: A large animal study.
Frontiers in physiology , 2022 | Pubmed ID: 36589429
Alterations in Cytoskeleton and Mitochondria in the Development and Reversal of Steatosis in Human Hepatocytes.
Cellular and molecular gastroenterology and hepatology Apr, 2023 | Pubmed ID: 37085137
Towards Optimizing Sub-Normothermic Machine Perfusion in Fasciocutaneous Flaps: A Large Animal Study.
Bioengineering (Basel, Switzerland) Dec, 2023 | Pubmed ID: 38136006
The Autonomization Principle in Vascularized Flaps: An Alternative Strategy for Composite Tissue Scaffold In Vivo Revascularization.
Bioengineering (Basel, Switzerland) Dec, 2023 | Pubmed ID: 38136031
Tissue engineering strategies for breast reconstruction: a literature review of current advances and future directions.
Annals of translational medicine Feb, 2024 | Pubmed ID: 38304901
Bote G. Bruinsma*,1,
James H. Avruch*,2,
Pepijn D. Weeder1,
Gautham V. Sridharan1,
Basak E. Uygun1,
Negin G. Karimian1,
Robert J. Porte3,
James F. Markmann2,
Heidi Yeh2,
Korkut Uygun1
1Center for Engineering in Medicine, Dept. of Surgery, Massachusetts General Hospital, Harvard Medical School,
2Transplant Center, Dept. of Surgery, Massachusetts General Hospital, Harvard Medical School,
3Section of Hepatobiliary Surgery and Liver Transplantation, Department of Surgery, University Medical Center Groningen, University of Groningen
Victor Pozzo1,2,4,
Golda Romano1,2,4,
Marion Goutard1,2,4,
Elise Lupon1,2,4,
Pierre Tawa1,2,4,
Aylin Acun3,4,5,
Alec R. Andrews2,
Corentin B. Taveau1,2,4,6,
Basak E. Uygun1,2,3,4,
Mark A. Randolph1,2,4,
Curtis L. Cetrulo1,2,4,
Alexandre G. Lellouch1,2,4,6
1Division of Plastic and Reconstructive Surgery, Massachusetts General Hospital, Harvard Medical School,
2Vascularized Composite Allotransplantation Laboratory, Center for Transplantation Sciences, Massachusetts General Hospital, Harvard Medical School,
3Center for Engineering in Medicine and Surgery, Massachusetts General Hospital, Harvard Medical School,
4, Shriners Hospital for Children,
5Department of Biomedical Engineering, Widener University,
6Service de Chirurgie Plastique, Hôpital Européen Georges Pompidou, Assistance Publique-Hôpitaux de Paris (APHP), Université Paris Descartes
Yanis Berkane*,1,2,3,5,
Austin Alana Shamlou*,1,2,4,5,
Jose Reyes1,2,
Hyshem H. Lancia1,2,5,
Irina Filz von Reiterdank1,2,5,6,7,
Nicolas Bertheuil3,
Basak E. Uygun2,5,6,
Korkut Uygun1,2,5,6,
William G. Austen Jr.2,4,
Curtis L. Cetrulo Jr.1,2,4,5,
Mark A. Randolph1,2,4,5,
Alexandre G. Lellouch1,2,5,6,8
1Vascularized Composite Allotransplantation Laboratory, Massachusetts General Hospital,
2, Harvard Medical School,
3Department of Plastic, Reconstructive and Aesthetic Surgery, Rennes University Hospital Center (CHU de Rennes), University of Rennes 1,
4Plastic Surgery Research Laboratory, Massachusetts General Hospital,
5, Shriners Children's Boston,
6Center for Engineering in Medicine and Surgery, Massachusetts General Hospital,
7Department of Plastic Surgery and Hand Surgery, University Medical Center Utrecht,
8Department of Plastic, Reconstructive, and Aesthetic Surgery, Groupe Almaviva Santé, Clinique de l'Alma
Yanis Berkane1,2,3,4,
Rohil Jain2,5,
Emmanuella O. Ajenu*,2,5,
Austin A. Shamlou*,1,2,
Khanh Nguyen2,5,
Michelle McCarthy1,2,5,
Basak E. Uygun2,5,
Alexandre G. Lellouch1,2,6,
Curtis L. Cetrulo Jr.1,2,
Korkut Uygun2,5,
Mark A. Randolph1,2,
Shannon N. Tessier2,5
1Vascularized Composite Allotransplantation Laboratory, Massachusetts General Hospital, Harvard Medical School,
2, Shriners Children’s Boston,
3Department of Plastic, Reconstructive and Aesthetic Surgery, Rennes University,
4SITI Laboratory, UMR, INSERM, Université de Rennes,
5Center for Engineering in Medicine and Surgery, Department of Surgery, Massachusetts General Hospital, Harvard Medical School,
6Innovative Therapies in Haemostasis, INSERM UMR-S, University of Paris
Laura Charlès1,2,3,
Thomas Agius*,4,5,
Irina Filz von Reiterdank*,1,2,3,6,
Janna Hagedorn1,2,3,
Yanis Berkane1,2,3,7,
Hyshem H. Lancia1,2,3,
Basak E. Uygun2,3,8,
Korkut Uygun2,3,8,
Curtis L. Cetrulo Jr.1,2,3,9,
Mark A. Randolph1,2,3,9,
Alexandre G. Lellouch1,2,3,8
1Vascularized Composite Allotransplantation Laboratory, Massachusetts General Hospital,
2, Harvard Medical School,
3, Shriners Children’s Boston,
4Center for Engineering in Medicine and Surgery, Massachusetts General Hospital,
5Department of Vascular Surgery, Centre Hospitalier Universitaire Vaudois and University of Lausanne,
6Department of Plastic, Reconstructive and Hand Surgery, University Medical Center Utrecht,
7Department of Plastic, Reconstructive and Aesthetic Surgery, Rennes University Hospital Center (CHU de Rennes), Rennes 1 University,
8Center for Engineering in Medicine and Surgery, Massachusetts General Hospital,
9Plastic Surgery Research Laboratory, Massachusetts General Hospital
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