Department of Pathology
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Whole-slide imaging and automated image analysis: considerations and opportunities in the practice of pathology.
Veterinary pathology Jan, 2014 | Pubmed ID: 24091812
Regulation of proximal T cell receptor signaling and tolerance induction by deubiquitinase Usp9X.
The Journal of experimental medicine Sep, 2014 | Pubmed ID: 25200027
Immunohistochemical detection of FLAG-tagged endogenous proteins in knock-in mice.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 04, 2015 | Pubmed ID: 25575566
Small molecule kinase inhibitors in veterinary oncology.
Veterinary journal (London, England : 1997) Aug, 2015 | Pubmed ID: 25744806
β-Cell Insulin Secretion Requires the Ubiquitin Ligase COP1.
Cell Dec, 2015 | Pubmed ID: 26627735
Inhibition of the kinase ITK in a mouse model of asthma reduces cell death and fails to inhibit the inflammatory response.
Science signaling Dec, 2015 | Pubmed ID: 26628680
NeuCode Proteomics Reveals Bap1 Regulation of Metabolism.
Cell reports 07, 2016 | Pubmed ID: 27373151
Transcriptional profiling of canine mast cell tumors: Searching for candidate targets and prognostic markers.
Veterinary journal (London, England : 1997) 08, 2016 | Pubmed ID: 27387731
Coordinated ubiquitination and phosphorylation of RIP1 regulates necroptotic cell death.
Cell death and differentiation 01, 2017 | Pubmed ID: 27518435
RIPK1 inhibits ZBP1-driven necroptosis during development.
Nature 12, 2016 | Pubmed ID: 27819682
Multifaceted Roles of Autophagy in Health and Disease.
Veterinary pathology 05, 2018 | Pubmed ID: 29635994
OTULIN limits cell death and inflammation by deubiquitinating LUBAC.
Nature 07, 2018 | Pubmed ID: 29950720
Observational Study Design in Veterinary Pathology, Part 1: Study Design.
Veterinary pathology 09, 2018 | Pubmed ID: 30071806
Kinase domain dimerization drives RIPK3-dependent necroptosis.
Science signaling 08, 2018 | Pubmed ID: 30131368
Detection of Necroptosis by Phospho-RIPK3 Immunohistochemical Labeling.
Methods in molecular biology (Clifton, N.J.) , 2018 | Pubmed ID: 30136239
The tumor suppressor BAP1 cooperates with BRAFV600E to promote tumor formation in cutaneous melanoma.
Pigment cell & melanoma research 03, 2019 | Pubmed ID: 30156010
The Hippo pathway effector TAZ induces TEAD-dependent liver inflammation and tumors.
Science signaling 09, 2018 | Pubmed ID: 30206136
Observational Study Design in Veterinary Pathology, Part 2: Methodology.
Veterinary pathology Sep, 2018 | Pubmed ID: 30227783
Ubiquitin ligase COP1 coordinates transcriptional programs that control cell type specification in the developing mouse brain.
Proceedings of the National Academy of Sciences of the United States of America 10, 2018 | Pubmed ID: 30322923
The Gag protein PEG10 binds to RNA and regulates trophoblast stem cell lineage specification.
PloS one , 2019 | Pubmed ID: 30951545
Intrinsic apoptosis shapes the tumor spectrum linked to inactivation of the deubiquitinase BAP1.
Science (New York, N.Y.) Apr, 2019 | Pubmed ID: 31000662
RIP1 inhibition blocks inflammatory diseases but not tumor growth or metastases.
Cell death and differentiation 01, 2020 | Pubmed ID: 31101885
Ubiquitin Ligases cIAP1 and cIAP2 Limit Cell Death to Prevent Inflammation.
Cell reports 05, 2019 | Pubmed ID: 31141691
Prognostic and predictive significance of KIT protein expression and c-kit gene mutation in canine cutaneous mast cell tumours: A consensus of the Oncology-Pathology Working Group.
Veterinary and comparative oncology Dec, 2019 | Pubmed ID: 31264352
Unobstructed Multiscale Imaging of Tissue Sections for Ultrastructural Pathology Analysis by Backscattered Electron Scanning Microscopy.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 01, 2020 | Pubmed ID: 31385742
Applications and considerations for the use of genetically engineered mouse models in drug development.
Cell and tissue research May, 2020 | Pubmed ID: 31486957
Cleavage of RIPK1 by caspase-8 is crucial for limiting apoptosis and necroptosis.
Nature 10, 2019 | Pubmed ID: 31511692
The RIPK4-IRF6 signalling axis safeguards epidermal differentiation and barrier function.
Nature 10, 2019 | Pubmed ID: 31578523
Activity of caspase-8 determines plasticity between cell death pathways.
Nature 11, 2019 | Pubmed ID: 31723262
RIP1 kinase activity is critical for skin inflammation but not for viral propagation.
Journal of leukocyte biology 06, 2020 | Pubmed ID: 31985117
The Tumor Suppressor BAP1 Regulates the Hippo Pathway in Pancreatic Ductal Adenocarcinoma.
Cancer research 04, 2020 | Pubmed ID: 31988076
MAP4K4 negatively regulates CD8 T cell-mediated antitumor and antiviral immunity.
Science immunology 03, 2020 | Pubmed ID: 32220977
Single-Cell Transcriptome Profiling of the Kidney Glomerulus Identifies Key Cell Types and Reactions to Injury.
Journal of the American Society of Nephrology : JASN 10, 2020 | Pubmed ID: 32651223
The Balance of TNF Mediated Pathways Regulates Inflammatory Cell Death Signaling in Healthy and Diseased Tissues.
Frontiers in cell and developmental biology , 2020 | Pubmed ID: 32671059
Ubiquitin Ligase COP1 Suppresses Neuroinflammation by Degrading c/EBPβ in Microglia.
Cell 09, 2020 | Pubmed ID: 32795415
Integration of innate immune signalling by caspase-8 cleavage of N4BP1.
Nature 11, 2020 | Pubmed ID: 32971525
Genetic inactivation of RIP1 kinase does not ameliorate disease in a mouse model of ALS.
Cell death and differentiation 03, 2021 | Pubmed ID: 32994544
Impaired RIPK1 ubiquitination sensitizes mice to TNF toxicity and inflammatory cell death.
Cell death and differentiation 03, 2021 | Pubmed ID: 32999468
NINJ1 mediates plasma membrane rupture during lytic cell death.
Nature 03, 2021 | Pubmed ID: 33472215
Genetic inactivation of RIP1 kinase activity in rats protects against ischemic brain injury.
Cell death & disease 04, 2021 | Pubmed ID: 33828080
Shigella ubiquitin ligase IpaH7.8 targets gasdermin D for degradation to prevent pyroptosis and enable infection.
Cell host & microbe 10, 2021 | Pubmed ID: 34492225
Reporting guidelines for manuscripts on tumor prognosis.
Veterinary pathology 05, 2022 | Pubmed ID: 35220838
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