Benjamin Combs

Heat shock protein 70 prevents both tau aggregation and the inhibitory effects of preexisting tau aggregates on fast axonal transport.

Gene Therapy Models of Alzheimer's Disease and Other Dementias.

Pathological conformations involving the amino terminus of tau occur early in Alzheimer's disease and are differentially detected by monoclonal antibodies.

Pseudophosphorylation of tau at S422 enhances SDS-stable dimer formation and impairs both anterograde and retrograde fast axonal transport.

Analysis of isoform-specific tau aggregates suggests a common toxic mechanism involving similar pathological conformations and axonal transport inhibition.

Exposure of the Amino Terminus of Tau Is a Pathological Event in Multiple Tauopathies.

Production of recombinant tau oligomers in vitro.

Axonal Degeneration in Tauopathies: Disease Relevance and Underlying Mechanisms.

FTDP-17 Mutations Alter the Aggregation and Microtubule Stabilization Propensity of Tau in an Isoform-Specific Fashion.

Tau and Axonal Transport Misregulation in Tauopathies.

Liquid-liquid phase separation induces pathogenic tau conformations in vitro.

Tau: A Signaling Hub Protein.

Frontotemporal Lobar Dementia Mutant Tau Impairs Axonal Transport through a Protein Phosphatase 1γ-Dependent Mechanism.

Age-dependent accumulation of tau aggregation in .

Phosphomimetics at Ser199/Ser202/Thr205 in Tau Impairs Axonal Transport in Rat Hippocampal Neurons.