Development and Aging Program,
NASCR Center,
Development and Aging Program, NASCR Center
Rolf Bodmer has not added Biography.
If you are Rolf Bodmer and would like to personalize this page please email our Author Liaison for assistance.
[The use of RNAi as a technique to study the functions of heart-related genes in Drosophila].
Yi chuan xue bao = Acta genetica Sinica Jan, 2002 | Pubmed ID: 11838373
The bereft gene, a potential target of the neural selector gene cut, contributes to bristle morphogenesis.
Genetics May, 2002 | Pubmed ID: 12019237
MBLR, a new RING finger protein resembling mammalian Polycomb gene products, is regulated by cell cycle-dependent phosphorylation.
Genes to cells : devoted to molecular & cellular mechanisms Aug, 2002 | Pubmed ID: 12167161
The patterns of wingless, decapentaplegic, and tinman position the Drosophila heart.
Mechanisms of development Jun, 2002 | Pubmed ID: 12175486
Transcriptional integration of competence modulated by mutual repression generates cell-type specificity within the cardiogenic mesoderm.
Developmental biology Dec, 2002 | Pubmed ID: 12482712
AmphiNk2-tin, an amphioxus homeobox gene expressed in myocardial progenitors: insights into evolution of the vertebrate heart.
Developmental biology Mar, 2003 | Pubmed ID: 12618138
Gata factor Pannier is required to establish competence for heart progenitor formation.
Development (Cambridge, England) Jul, 2003 | Pubmed ID: 12756184
Myogenic cells fates are antagonized by Notch only in asymmetric lineages of the Drosophila heart, with or without cell division.
Development (Cambridge, England) Jul, 2003 | Pubmed ID: 12756185
Dynamics of Cux2 expression suggests that an early pool of SVZ precursors is fated to become upper cortical layer neurons.
Cerebral cortex (New York, N.Y. : 1991) Dec, 2004 | Pubmed ID: 15238450
Screening assays for heart function mutants in Drosophila.
BioTechniques Jul, 2004 | Pubmed ID: 15283201
Drosophila, an emerging model for cardiac disease.
Gene Nov, 2004 | Pubmed ID: 15527959
Insulin regulation of heart function in aging fruit flies.
Nature genetics Dec, 2004 | Pubmed ID: 15565107
Neuromancer Tbx20-related genes (H15/midline) promote cell fate specification and morphogenesis of the Drosophila heart.
Developmental biology Mar, 2005 | Pubmed ID: 15733676
Identification of genetic loci that interact with cut during Drosophila wing-margin development.
Genetics Aug, 2005 | Pubmed ID: 15956666
Embryonic even skipped-dependent muscle and heart cell fates are required for normal adult activity, heart function, and lifespan.
Circulation research Nov, 2005 | Pubmed ID: 16239588
Slit and Robo control cardiac cell polarity and morphogenesis.
Current biology : CB Dec, 2005 | Pubmed ID: 16360689
Hedgehog and RAS pathways cooperate in the anterior-posterior specification and positioning of cardiac progenitor cells.
Developmental biology Feb, 2006 | Pubmed ID: 16387294
Role of svp in Drosophila pericardial cell growth.
Yi chuan xue bao = Acta genetica Sinica Jan, 2006 | Pubmed ID: 16450585
Images in cardiovascular medicine: in vivo imaging of the adult Drosophila melanogaster heart with real-time optical coherence tomography.
Circulation Jul, 2006 | Pubmed ID: 16831991
The ATP-sensitive potassium (KATP) channel-encoded dSUR gene is required for Drosophila heart function and is regulated by tinman.
Proceedings of the National Academy of Sciences of the United States of America Aug, 2006 | Pubmed ID: 16882722
Activated FOXO-mediated insulin resistance is blocked by reduction of TOR activity.
Cell metabolism Aug, 2006 | Pubmed ID: 16890541
Antioxidants protect PINK1-dependent dopaminergic neurons in Drosophila.
Proceedings of the National Academy of Sciences of the United States of America Sep, 2006 | Pubmed ID: 16938835
Functional conservation of zinc-finger homeodomain gene zfh1/SIP1 in Drosophila heart development.
Development genes and evolution Nov, 2006 | Pubmed ID: 16957952
Cardioblast-intrinsic Tinman activity controls proper diversification and differentiation of myocardial cells in Drosophila.
Development (Cambridge, England) Oct, 2006 | Pubmed ID: 16987868
Age-related cardiac disease model of Drosophila.
Mechanisms of ageing and development Jan, 2007 | Pubmed ID: 17125816
Drosophila aging 2005/06.
Experimental gerontology Dec, 2006 | Pubmed ID: 17126511
Age-related cardiac deterioration: insights from Drosophila.
Frontiers in bioscience : a journal and virtual library , 2007 | Pubmed ID: 17127282
Cardiac aging.
Seminars in cell & developmental biology Feb, 2007 | Pubmed ID: 17275368
KCNQ potassium channel mutations cause cardiac arrhythmias in Drosophila that mimic the effects of aging.
Proceedings of the National Academy of Sciences of the United States of America Mar, 2007 | Pubmed ID: 17360457
Genetic control of heart function and aging in Drosophila.
Trends in cardiovascular medicine Jul, 2007 | Pubmed ID: 17574126
Genetic variation for cardiac dysfunction in Drosophila.
PloS one , 2007 | Pubmed ID: 17622346
Myosin transducer mutations differentially affect motor function, myofibril structure, and the performance of skeletal and cardiac muscles.
Molecular biology of the cell Feb, 2008 | Pubmed ID: 18045988
Drosophila aging 2006/2007.
Experimental gerontology Jan, 2008 | Pubmed ID: 18061385
Spatial specificity of mesodermal even-skipped expression relies on multiple repressor sites.
Developmental biology Jan, 2008 | Pubmed ID: 18067885
The Drosophila muscle LIM protein, Mlp84B, is essential for cardiac function.
The Journal of experimental biology Jan, 2008 | Pubmed ID: 18083727
ZNF418, a novel human KRAB/C2H2 zinc finger protein, suppresses MAPK signaling pathway.
Molecular and cellular biochemistry Mar, 2008 | Pubmed ID: 18084723
Dystrophin deficiency in Drosophila reduces lifespan and causes a dilated cardiomyopathy phenotype.
Aging cell Mar, 2008 | Pubmed ID: 18221418
Dispensable role of Drosophila ortholog of LRRK2 kinase activity in survival of dopaminergic neurons.
Molecular neurodegeneration , 2008 | Pubmed ID: 18257932
A novel human BTB-kelch protein KLHL31, strongly expressed in muscle and heart, inhibits transcriptional activities of TRE and SRE.
Molecules and cells Nov, 2008 | Pubmed ID: 18719355
Transcription factor neuromancer/TBX20 is required for cardiac function in Drosophila with implications for human heart disease.
Proceedings of the National Academy of Sciences of the United States of America Dec, 2008 | Pubmed ID: 19074289
The Drosophila homolog of vertebrate Islet1 is a key component in early cardiogenesis.
Development (Cambridge, England) Jan, 2009 | Pubmed ID: 19088091
Non-autonomous modulation of heart rhythm, contractility and morphology in adult fruit flies.
Developmental biology Apr, 2009 | Pubmed ID: 19233157
A new method for detection and quantification of heartbeat parameters in Drosophila, zebrafish, and embryonic mouse hearts.
BioTechniques Feb, 2009 | Pubmed ID: 19317655
Partial loss of GATA factor Pannier impairs adult heart function in Drosophila.
Human molecular genetics Sep, 2009 | Pubmed ID: 19494035
d4eBP acts downstream of both dTOR and dFoxo to modulate cardiac functional aging in Drosophila.
Aging cell Sep, 2009 | Pubmed ID: 19594484
KBTBD7, a novel human BTB-kelch protein, activates transcriptional activities of SRE and AP-1.
BMB reports Jan, 2010 | Pubmed ID: 20132730
Sestrin as a feedback inhibitor of TOR that prevents age-related pathologies.
Science (New York, N.Y.) Mar, 2010 | Pubmed ID: 20203043
A global in vivo Drosophila RNAi screen identifies NOT3 as a conserved regulator of heart function.
Cell Apr, 2010 | Pubmed ID: 20371351
SAMD4B, a novel SAM-containing protein, inhibits AP-1-, p53- and p21-mediated transcriptional activity.
BMB reports May, 2010 | Pubmed ID: 20510020
Sestrins at the crossroad between stress and aging.
Aging Jun, 2010 | Pubmed ID: 20606249
High-fat-diet-induced obesity and heart dysfunction are regulated by the TOR pathway in Drosophila.
Cell metabolism Nov, 2010 | Pubmed ID: 21035763
Drosophila as a model to study cardiac aging.
Experimental gerontology May, 2011 | Pubmed ID: 21130861
Phospholipid homeostasis regulates lipid metabolism and cardiac function through SREBP signaling in Drosophila.
Genes & development Jan, 2011 | Pubmed ID: 21245170
Phospholipid homeostasis and lipotoxic cardiomyopathy: a matter of balance.
Fly Jul-Sep, 2011 | Pubmed ID: 21494094
A mighty small heart: the cardiac proteome of adult Drosophila melanogaster.
PloS one , 2011 | Pubmed ID: 21541028
Tinman/Nkx2-5 acts via miR-1 and upstream of Cdc42 to regulate heart function across species.
The Journal of cell biology Jun, 2011 | Pubmed ID: 21690310
ATP-sensitive potassium channel (K(ATP))-dependent regulation of cardiotropic viral infections.
Proceedings of the National Academy of Sciences of the United States of America Jul, 2011 | Pubmed ID: 21719711
The UNC-45 chaperone is critical for establishing myosin-based myofibrillar organization and cardiac contractility in the Drosophila heart model.
PloS one , 2011 | Pubmed ID: 21799905
Lipotoxicity and cardiac dysfunction in mammals and Drosophila.
Critical reviews in biochemistry and molecular biology Oct, 2011 | Pubmed ID: 21851295
Over-expression of DSCAM and COL6A2 cooperatively generates congenital heart defects.
PLoS genetics Nov, 2011 | Pubmed ID: 22072978
Measuring passive myocardial stiffness in Drosophila melanogaster to investigate diastolic dysfunction.
Journal of cellular and molecular medicine Jan, 2012 | Pubmed ID: 22225769
Probing the polygenic basis of cardiomyopathies in Drosophila.
Journal of cellular and molecular medicine Jan, 2012 | Pubmed ID: 22268758
Drosophila as a Model to Study the Genetic Mechanisms of Obesity-Associated Heart Dysfunction.
Journal of cellular and molecular medicine Feb, 2012 | Pubmed ID: 22303936
Regulation of parkin and PINK1 by neddylation.
Human molecular genetics Jun, 2012 | Pubmed ID: 22388932
Statin treatment increases lifespan and improves cardiac health in Drosophila by decreasing specific protein prenylation.
PloS one , 2012 | Pubmed ID: 22737247
APJ acts as a dual receptor in cardiac hypertrophy.
Nature Aug, 2012 | Pubmed ID: 22810587
A Drosophila model of high sugar diet-induced cardiomyopathy.
PLoS genetics , 2013 | Pubmed ID: 23326243
Declining signal-dependence of Nrf2-MafS regulated gene expressioncorrelates with aging phenotypes.
Aging cell Mar, 2013 | Pubmed ID: 23521918
Complex genetic architecture of cardiac disease in a wild type inbred strain of Drosophila melanogaster.
PloS one , 2013 | Pubmed ID: 23638165
Whole-Genome rVISTA: a tool to determine enrichment of transcription factor binding sites in gene promoters from transcriptomic data.
Bioinformatics (Oxford, England) Aug, 2013 | Pubmed ID: 23736530
Survival response to increased ceramide involves metabolic adaptation through novel regulators of glycolysis and lipolysis.
PLoS genetics Jun, 2013 | Pubmed ID: 23818862
Multiplexin promotes heart but not aorta morphogenesis by polarized enhancement of slit/robo activity at the heart lumen.
PLoS genetics Jun, 2013 | Pubmed ID: 23825967
Pygopus maintains heart function in aging Drosophila independently of canonical Wnt signaling.
Circulation. Cardiovascular genetics Oct, 2013 | Pubmed ID: 24046329
Mechanical and non-mechanical functions of Dystrophin can prevent cardiac abnormalities in Drosophila.
Experimental gerontology Jan, 2014 | Pubmed ID: 24231130
The role of pygopus in the differentiation of intracardiac valves in Drosophila.
Genesis (New York, N.Y. : 2000) Jan, 2014 | Pubmed ID: 24265259
Integrin-linked kinase modulates longevity and thermotolerance in C. elegans through neuronal control of HSF-1.
Aging cell Jun, 2014 | Pubmed ID: 24314125
Huntington's disease induced cardiac amyloidosis is reversed by modulating protein folding and oxidative stress pathways in the Drosophila heart.
PLoS genetics , 2013 | Pubmed ID: 24367279
A dual role for integrin-linked kinase and β1-integrin in modulating cardiac aging.
Aging cell Jun, 2014 | Pubmed ID: 24400780
Metabolic and transcriptional response to a high-fat diet in Drosophila melanogaster.
Molecular metabolism Feb, 2014 | Pubmed ID: 24567903
ROS regulate cardiac function via a distinct paracrine mechanism.
Cell reports Apr, 2014 | Pubmed ID: 24656823
Systems genomics of metabolic phenotypes in wild-type Drosophila melanogaster.
Genetics Jun, 2014 | Pubmed ID: 24671769
Methods to assess Drosophila heart development, function and aging.
Methods (San Diego, Calif.) Jun, 2014 | Pubmed ID: 24727147
Cdc42 and formin activity control non-muscle myosin dynamics during Drosophila heart morphogenesis.
The Journal of cell biology Sep, 2014 | Pubmed ID: 25267295
Notch Activation of Ca(2+) Signaling in the Development of Hypoxic Pulmonary Vasoconstriction and Pulmonary Hypertension.
American journal of respiratory cell and molecular biology Sep, 2015 | Pubmed ID: 25569851
PGC-1/Spargel Counteracts High-Fat-Diet-Induced Obesity and Cardiac Lipotoxicity Downstream of TOR and Brummer ATGL Lipase.
Cell reports Mar, 2015 | Pubmed ID: 25753422
Cardiac deficiency of single cytochrome oxidase assembly factor scox induces p53-dependent apoptosis in a Drosophila cardiomyopathy model.
Human molecular genetics Jul, 2015 | Pubmed ID: 25792727
Clueless, a protein required for mitochondrial function, interacts with the PINK1-Parkin complex in Drosophila.
Disease models & mechanisms Jun, 2015 | Pubmed ID: 26035866
Genetic manipulation of cardiac ageing.
The Journal of physiology Apr, 2016 | Pubmed ID: 26060055
Vinculin network-mediated cytoskeletal remodeling regulates contractile function in the aging heart.
Science translational medicine Jun, 2015 | Pubmed ID: 26084806
Obesity-associated cardiac dysfunction in starvation-selected Drosophila melanogaster.
American journal of physiology. Regulatory, integrative and comparative physiology Sep, 2015 | Pubmed ID: 26136533
Cellular Mechanisms of Drosophila Heart Morphogenesis.
Journal of cardiovascular development and disease Mar, 2015 | Pubmed ID: 26236710
Klf15 Is Critical for the Development and Differentiation of Drosophila Nephrocytes.
PloS one , 2015 | Pubmed ID: 26301956
Cardiac responses to hypoxia and reoxygenation in Drosophila.
American journal of physiology. Regulatory, integrative and comparative physiology Dec, 2015 | Pubmed ID: 26377557
Gaining Insights into Diabetic Cardiomyopathy from Drosophila.
Trends in endocrinology and metabolism: TEM Nov, 2015 | Pubmed ID: 26482877
SPARC-Dependent Cardiomyopathy in Drosophila.
Circulation. Cardiovascular genetics Apr, 2016 | Pubmed ID: 26839388
Drosophila as a potential model to ameliorate mutant Huntington-mediated cardiac amyloidosis.
Rare diseases (Austin, Tex.) , 2014 | Pubmed ID: 26942103
High throughput physiological screening of iPSC-derived cardiomyocytes for drug development.
Biochimica et biophysica acta Jul, 2016 | Pubmed ID: 26952934
The canonical Wingless signaling pathway is required but not sufficient for inflow tract formation in the Drosophila melanogaster heart.
Developmental biology May, 2016 | Pubmed ID: 26983369
A Restrictive Cardiomyopathy Mutation in an Invariant Proline at the Myosin Head/Rod Junction Enhances Head Flexibility and Function, Yielding Muscle Defects in Drosophila.
Journal of molecular biology Jun, 2016 | Pubmed ID: 27107639
52 Genetic Loci Influencing Myocardial Mass.
Journal of the American College of Cardiology Sep, 2016 | Pubmed ID: 27659466
Extracellular matrix downregulation in the Drosophila heart preserves contractile function and improves lifespan.
Matrix biology : journal of the International Society for Matrix Biology Oct, 2017 | Pubmed ID: 27793636
Expression patterns of cardiac aging in Drosophila.
Aging cell Feb, 2017 | Pubmed ID: 28090760
Modest overexpression of FOXO maintains cardiac proteostasis and ameliorates age-associated functional decline.
Aging cell Feb, 2017 | Pubmed ID: 28090761
Experimental Evolution and Heart Function in Drosophila.
Physiological and biochemical zoology : PBZ Mar/Apr, 2017 | Pubmed ID: 28277957
Morphological differentiation of the embryonic peripheral neurons in Drosophila.
Roux's archives of developmental biology : the official organ of the EDBO Feb, 1987 | Pubmed ID: 28305460
A late role for a subset of neurogenic genes to limit sensory precursor recruitments in Drosophila embryos.
Roux's archives of developmental biology : the official organ of the EDBO Aug, 1993 | Pubmed ID: 28306050
SLP-2 interacts with Parkin in mitochondria and prevents mitochondrial dysfunction in Parkin-deficient human iPSC-derived neurons and Drosophila.
Human molecular genetics Jul, 2017 | Pubmed ID: 28379402
Transcriptomic analysis identifies a role of PI3K-Akt signalling in the responses of skeletal muscle to acute hypoxia in vivo.
The Journal of physiology Sep, 2017 | Pubmed ID: 28688178
JoVE 소개
Copyright © 2024 MyJoVE Corporation. 판권 소유