The overall goal of this procedure is to safely and accurately deliver a volume of injectate into the left ventricular myocardium of the rabbit heart. And to do this by taking advantage of percutaneous contrast echocardiography guidance. This is a
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Novel therapeutic strategies in cardiac regenerative medicine require extensive and detailed studies in large preclinical animal models before they can be considered for use in humans. Here, we demonstrate a percutaneous contrast echocardiography-guided intramyocardial injection technique in rabbits, which is valuable for hypothesis testing the efficacy of such novel therapies.