In Vitro Directed Evolution of a Restriction Endonuclease with More Stringent Specificity

Design and Use of a Low Cost, Automated Morbidostat for Adaptive Evolution of Bacteria Under Antibiotic Drug Selection

9.6K Views

Procedure for Adaptive Laboratory Evolution of Microorganisms Using a Chemostat

14.1K Views

Genome Editing and Directed Differentiation of hPSCs for Interrogating Lineage Determinants in Human Pancreatic Development

13.0K Views

Generation of a Gene-disrupted Streptococcus mutans Strain Without Gene Cloning

7.6K Views

Testing the Role of Multicopy Plasmids in the Evolution of Antibiotic Resistance

11.5K Views

Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry

10.0K Views

Genome-wide Surveillance of Transcription Errors in Eukaryotic Organisms

9.4K Views

Producing Gene Deletions in Escherichia coli by P1 Transduction with Excisable Antibiotic Resistance Cassettes

16.9K Views

Using In Vitro and In-cell SHAPE to Investigate Small Molecule Induced Pre-mRNA Structural Changes

8.2K Views

Using Sniper-Cas9 to Minimize Off-target Effects of CRISPR-Cas9 Without the Loss of On-target Activity Via Directed Evolution

9.6K Views