Using Nicotine in a Silica-Exposed Mouse Model to Promote Lung Epithelial-Mesenchymal Transition

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664 Views

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06:12 min

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March 3rd, 2023

DOI :

10.3791/65127-v

March 3rd, 2023

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Haoming Chen*¹^,²^,³^,⁴, Bing Li*¹^,²^,³^,⁴, Hangbing Cao¹^,²^,³^,⁴, Yehong Zhao¹^,²^,³^,⁴, Yuanjie Zou¹^,²^,³^,⁴, Wenyang Wang¹^,²^,³^,⁴, Min Mu¹^,²^,³^,⁴, Xinrong Tao¹^,²^,³^,⁴

¹Key Laboratory of Industrial Dust Control and Occupational Health of the Ministry of Education, Anhui University of Science and Technology, ²Key Laboratory of Industrial Dust Deep Reduction and Occupational Health and Safety of Anhui Higher Education Institutes, Anhui University of Science and Technology, ³Anhui Province Engineering Laboratory of Occupational Health and Safety, ⁴School of Medicine, Department of Medical Frontier Experimental Center, Anhui University of Science and Technology

Podsumowanie

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Nicotine

Silica Exposure

Lung Epithelial mesenchymal Transition

Mouse Model

Chronic Nicotine Ingestion

Lung Fibroses

Nasal Drip

Crystalline Silica Suspension

Rozdziały w tym wideo

0:04

Introduction

0:37

Preparation of Silica Suspension and Injection

1:44

Mouse Capture and Nicotine Exposure

2:44

Harvesting Fresh and Fixed Lung Tissues

4:35

Results: Analysis of Nicotine‐Silica Exposed Mice s Lung Tissue

5:42

Conclusion

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