Results: Assessment of CART Cell‐Associated Toxicities in a PDX Mice Model
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Conclusion
Transcrição
This protocol utilizes human CAR-T and tumor cells and accurately demonstrates the toxicities associated with CART19 administration. Therefore, recapitulating what has been observed in the clinic. The main advantage of using this platform is that
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Here, we describe a protocol in which an acute lymphoblastic leukemia patient-derived xenograft model is used as a strategy to assess and monitor CD19-targeted chimeric antigen receptor T cell-associated toxicities.