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In This Article

  • Summary
  • Abstract
  • Introduction
  • Protocol
  • Representative Results
  • Discussion
  • Acknowledgements
  • Materials
  • References
  • Reprints and Permissions

Summary

This protocol outlines the use of point-of-care ultrasound (POCUS) to monitor patients on peripheral veno-arterial extracorporeal membrane oxygenation (V-A ECMO) without left ventricular venting. It evaluates left ventricular distension, intracardiac or aortic root thrombus, and identifies useful cardiac POCUS parameters for weaning from V-A ECMO.

Abstract

Over the past several decades, veno-arterial extracorporeal membrane oxygenation (V-A ECMO) has become a critical tool in the management of patients with severe cardiogenic shock and cardiopulmonary failure. Due to the inherent instability of these patients, their transport away from intensive care units is fraught with risk. As a result, bedside diagnostic tools are essential for their daily care. One such tool is point-of-care ultrasound (POCUS) of the heart, which can non-invasively assess several parameters: left ventricular (LV) performance (size, systolic function, stroke volume, aortic valve opening), right ventricular (RV) performance (size, systolic function), and the presence of intracardiac thrombus. Additionally, POCUS can assist in evaluating readiness for V-A ECMO weaning and eventual decannulation. Despite its potential, the use of POCUS in the context of V-A ECMO remains inconsistent due to variability in provider training. This study aims to address this gap by detailing POCUS image acquisition in V-A ECMO, particularly in the absence of LV venting. It covers key aspects such as patient positioning, transducer selection, probe placement, acquisition sequence, and image optimization.

Introduction

Extracorporeal membrane oxygenation (ECMO) is a potentially life-saving temporizing strategy for patients, which has seen an ever-increasing utilization rate1,2. ECMO has two different configurations: veno-venous (V-V) and veno-arterial (V-A). Over the past several decades, V-A ECMO has emerged as a fundamental tool in the care of patients with severe cardiogenic shock and cardiopulmonary failure3,4,5,6. The two cannulation strategies for V-A ECMO are central and peripheral

Protocol

All procedures performed in studies involving human participants were in accordance with the ethical standards of the Vanderbilt University Medical Center institutional research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards. The protocol was derived after a review of the published literature by an expert panel of intensivists16,21,22,23

Representative Results

This article describes the interpretation of point-of-care cardiac ultrasound in patients supported on peripheral V-A ECMO in two clinical scenarios: (1) As a monitoring tool during ECMO support to assess for the presence of left ventricular (LV) distension and the presence of intracardiac or aortic root thrombus, and (2) as a screening tool to evaluate readiness from liberation of mechanical support.

There is no single accepted.......

Discussion

Significance with respect to existing methods
The utilization of V-A ECMO as a rescue therapy for acute decompensated cardiac failure has been on the rise1. Peripheral V-A ECMO is utilized as a temporary intervention to allow time for the acutely failing heart to recover while optimizing end-organ function2,3. Although there is a lack of established guidelines regarding the application of echocardiography in the cont.......

Acknowledgements

This work was supported in part by the Center for Experiential Learning and Assessment (CELA) at Vanderbilt University Medical Center (VUMC), Nashville, TN, USA.  The authors would also like to thank the staff, faculty, and personal at CELA for their guidance, assistance, and support throughout this project.  Any opinions, findings, conclusions, or recommendations expressed in this publication are those of the authors and do not necessarily reflect the views of CELA or VUMC.

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Materials

NameCompanyCatalog NumberComments
Affiniti PhilipsAffiniti 70
Edge 1 ultrasound machineSonoSiteEdge II
Vivid iqGE

References

  1. Guglin, M. et al. Venoarterial ECMO for adults. J Am Coll Cardiol. 73 (6), 698-716 (2019).
  2. Extracorporeal Life Support Organization (ELSO). ELSO General Guidelines for all ECLS Cases. Version 1.4. Extracorporeal Life Support Organization, Ann Arbor, MI, USA, (2017).
  3. Lorusso, R. et al. ELSO interim guidelines for venoarterial extracorporeal membrane oxygenation in adult cardiac patients. ASAIO J. 67 (8), 827-844 (2021).
  4. Combes, A., Price, S., Slutsky, A. S., Brodie, D. Temporary circulatory support for cardiogenic shock. Lancet. 396 (10245), 199-212 (2020).
  5. ....

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Extracorporeal membrane oxygenationV A ECMOMechanical circulatory supportEchocardiographyUltrasoundMonitoring

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