Assemble PEG-bl-PPS Nanocarriers via Hand-Powered Flash Nanoprecipitation
4:18
Fabricate Polymersomes via Flash Nanoprecipitation (FNP) Using the Custom-Made High-Speed Syringe Pump
5:27
Results: Monodisperse Polymersome Formation and Loading
6:12
Conclusion
Transkript
We believe that the use of flash nanoprecipitation to assemble complex nanostructures will allow researchers who do not have extensive experience in chemistry, engineering or nanomaterial science to fabricate advanced drug delivery systems indepen
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Nanomaterials provide versatile mechanisms of controlled therapeutic delivery for both basic science and translational applications, but their fabrication often requires expertise that is unavailable in most biomedical laboratories. Here, we present protocols for the scalable fabrication and therapeutic loading of diverse self-assembled nanocarriers using flash nanoprecipitation.