Results: Characterization of the Synthesized Peptides
6:32
Conclusion
Transkript
In this protocol, the sulfonium salt was constructed that could act as a new hand that reacted with the protein cysteine on the special proximity. The advantage of this technique was that this reaction was fast and efficient, and Met-catalyst free
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This protocol presents the synthesis of cyclic peptides via bisalkylation between cysteine and methionine and the facile thiol-yne reaction triggered by the propargyl sulfonium center.