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Experimental Models for Study of Retinal Pigment Epithelial Physiology and Pathophysiology

DOI :

10.3791/2032-v

8:28 min

November 6th, 2010

November 6th, 2010

18,839 Views

1National Eye Institute, National Institutes of Health

We provide a reproducible method for culturing confluent monolayers of human fetal retinal pigment epithelial cells (hfRPE) cells that exhibit morphology, physiology, polarity, and protein and gene expression patterns of adult native tissue. This work has been extended to an animal model of several eye diseases.

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Retinal Pigment Epithelium

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