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Retinal Explant of the Adult Mouse Retina as an Ex Vivo Model for Studying Retinal Neurovascular Diseases

DOI :

10.3791/63966-v

December 9th, 2022

December 9th, 2022

2,847 Views

1Eye Research Center and Department of Foundational Medical Studies, Oakland University William Beaumont School of Medicine, 2Eye Research Institute, Oakland University, 3Human Anatomy and Embryology Department, Mansoura Faculty of Medicine, Mansoura University

This protocol presents and describes steps for the isolation, dissection, culturing, and staining of retinal explants obtained from an adult mouse. This method is beneficial as an ex vivo model for studying different retinal neurovascular diseases such as diabetic retinopathy.

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