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Delivery of Therapeutic Agents Through Intracerebroventricular (ICV) and Intravenous (IV) Injection in Mice

DOI :

10.3791/2968-v

October 3rd, 2011

October 3rd, 2011

57,109 Views

1Department of Molecular Microbiology and Immunology, Bond Life Sciences Center, University of Missouri, 2Department of Biological Sciences, Columbia University , 3Department of Veterinary Pathobiology, Bond Life Sciences Center, University of Missouri

This article demonstrates two very different methods of injection: 1) into the brain (intracerebroventricular) and 2) systemic (intravenous) to introduce the therapeutic agents into the central nervous system of neonatal mice.

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Intracerebroventricular Injection

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