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Studying Age-dependent Genomic Instability using the S. cerevisiae Chronological Lifespan Model

DOI :

10.3791/3030-v

8:46 min

September 29th, 2011

September 29th, 2011

15,202 Views

1Andrus Gerontology Center, Department of Biological Sciences, Department of Molecular and Computational Biology, University of Southern California, Los Angeles

Here we describe a set of DNA mutation assays that can be combined with the yeast chronological life span model to study the genes/pathways that regulate or contribute to genomic DNA instability during aging.

Tags

Age dependent Genomic Instability

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