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An In Vitro Model for Measuring Immune Responses to Malaria in the Context of HIV Co-infection

DOI :

10.3791/52969-v

October 6th, 2015

October 6th, 2015

10,169 Views

1Department of Biological Sciences, University of Calgary, 2Toronto General Research Institute, University Health Network

Human co-infection is difficult to replicate in vitro. However, human malaria parasites can readily be cultured in vitro, as can freshly isolated human peripheral blood mononuclear cells naturally infected with HIV. This provides an excellent model for studying early immune responses to malaria parasites in the context of HIV co-infection.

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Keywords In Vitro Model

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