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Expanding Cytotoxic T Lymphocytes from Umbilical Cord Blood that Target Cytomegalovirus, Epstein-Barr Virus, and Adenovirus

DOI :

10.3791/3627-v

May 7th, 2012

May 7th, 2012

12,578 Views

1Center for Cell and Gene Therapy, Baylor College of Medicine , 2Pathology and Immunology, Baylor College of Medicine , 3Department of Stem Cell Transplantation and Cellular Therapy, University of Texas M.D. Anderson Cancer Center, 4Medicine, Baylor College of Medicine , 5Department of Pediatrics, Baylor College of Medicine

Here we describe the first good manufacturing practice (GMP)-compliant method of producing virus-specific cytotoxic T lymphocytes (CTL) from umbilical cord blood, a source of predominantly naîve T cells.

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Cytotoxic T Lymphocytes

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