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Detection of MicroRNAs in Microglia by Real-time PCR in Normal CNS and During Neuroinflammation

DOI :

10.3791/4097-v

July 23rd, 2012

July 23rd, 2012

19,120 Views

1Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School

Microglia are resident macrophages that provide the first line of defense and immune surveillance of the central nervous system. MicroRNAs are regulatory molecules that play an important role in many physiological processes including activation and differentiation of macrophages. In this article, we describe the method for measurement of microRNAs in microglia.

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