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In Vivo Imaging Systems (IVIS) Detection of a Neuro-Invasive Encephalitic Virus

DOI :

10.3791/4429-v

December 2nd, 2012

December 2nd, 2012

20,245 Views

1Experimental Pathology, University of Texas Medical Branch

Utilizing luciferase and in vivo imaging systems (IVIS) as a novel means to identify disease endpoints before clinical developments occur. IVIS has allowed us to visualize in real time the invasion of encephalitic viruses over multiple days, providing a more accurate disease model for future study. It has also allowed us to identify the potential protective features of antivirals and vaccines faster than currently utilized animal models. The capability to utilize individual animals over multiple time points ensures reduc

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