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Assessment of Ovarian Cancer Spheroid Attachment and Invasion of Mesothelial Cells in Real Time

DOI :

10.3791/51655-v

14:25 min

May 20th, 2014

May 20th, 2014

17,005 Views

1Reproductive Development and Cancer Laboratory, MIMR-PHI Institute of Medical Research, 2Department of Developmental Biology and Anatomy, Monash University

Ovarian cancer cell invasion into the mesothelial lining of the peritoneum is a dynamic process over time. Utilizing a real time analyzer, the invasive capacity of ovarian cancer cells in a spheroid-mesothelial cell co-culture model can be quantified over prolonged time periods, providing insights into factors regulating the metastatic process.

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Keywords Ovarian Cancer

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