JoVE Logo
Faculty Resource Center

Sign In

Three-Dimensional (3D) Tumor Spheroid Invasion Assay

DOI :

10.3791/52686-v

12:19 min

May 1st, 2015

May 1st, 2015

55,014 Views

1Division of Molecular Pathology, The Institute of Cancer Research, 2Division of Cancer Therapeutics, The Institute of Cancer Research

Invasion of surrounding normal tissues is a defining characteristic of malignant tumors. We provide here a simple, semi-automated micro-plate assay of invasion into a natural 3D biomatrix that has been exemplified with a number of models of advanced human cancers.

Tags

Keywords 3D Tumor Spheroid

-- Views

Related Videos

article

Spheroid Assay to Measure TGF-β-induced Invasion

article

Human Neuroendocrine Tumor Cell Lines as a Three-Dimensional Model for the Study of Human Neuroendocrine Tumor Therapy

article

Coculture System with an Organotypic Brain Slice and 3D Spheroid of Carcinoma Cells

article

Quantification of Breast Cancer Cell Invasiveness Using a Three-dimensional (3D) Model

article

Assessment of Ovarian Cancer Spheroid Attachment and Invasion of Mesothelial Cells in Real Time

article

Three-dimensional Co-culture Model for Tumor-stromal Interaction

article

A Cancer Cell Spheroid Assay to Assess Invasion in a 3D Setting

article

Three-dimensional Alginate-bead Culture of Human Pituitary Adenoma Cells

article

Three-Dimensional Culture Assay to Explore Cancer Cell Invasiveness and Satellite Tumor Formation

article

Three-Dimensional Printing of a Complex Aortic Anomaly

JoVE Logo

Privacy

Terms of Use

Policies

Research

Education

ABOUT JoVE

Copyright © 2024 MyJoVE Corporation. All rights reserved