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Hydrogel Nanoparticle Harvesting of Plasma or Urine for Detecting Low Abundance Proteins

DOI :

10.3791/51789-v

August 7th, 2014

August 7th, 2014

13,731 Views

1Center for Applied Proteomics and Molecular Medicine, George Mason University, 2Ceres Nanosciences

Several pathological biomarkers cannot be easily detected by current techniques because of their low concentration in biological fluids, the presence of degrading enzymes, and large amounts of high molecular weight proteins. Chemically functionalized hydrogel nanoparticles can harvest, preserve and concentrate low abundance proteins enabling the detection of previously undetectable biomarkers.

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Hydrogel Nanoparticle

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