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Orthotopic Injection of Breast Cancer Cells into the Mammary Fat Pad of Mice to Study Tumor Growth.

DOI :

10.3791/51967-v

February 8th, 2015

February 8th, 2015

77,106 Views

1Department of Hemostasis and Thrombosis, Leiden University Medical Center

Cancer is a complex disease that is influenced by the tissue surrounding the tumor as well as local pro- and anti-inflammatory mediators. Therefore, orthotropic injection models, rather than subcutaneous models may be useful to study cancer progression in a manner that better mimics human pathology.

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Orthotopic Injection

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