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Metal-free Synthesis of Ynones from Acyl Chlorides and Potassium Alkynyltrifluoroborate Salts

DOI :

10.3791/52401-v

9:58 min

February 24th, 2015

February 24th, 2015

10,829 Views

1Faculty of Science, University of Ontario Institute of Technology

The goal of this manuscript is to demonstrate a straightforward method for the preparation of ynones from acyl chloride and potassium alkynyltrifluoroborate salt starting materials. The one-pot reaction proceeds rapidly in the presence of boron trichloride without exclusion of air and moisture.

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Metal free Synthesis

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