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Generation of Heterogeneous Drug Gradients Across Cancer Populations on a Microfluidic Evolution Accelerator for Real-Time Observation

DOI :

10.3791/60185-v

September 19th, 2019

September 19th, 2019

6,183 Views

1Princeton University, 2Johns Hopkins Medical Institute

We present a microfluidic cancer-on-chip model, the "Evolution Accelerator" technology, which provides a controllable platform for long-term real-time quantitative studies of cancer dynamics within well-defined environmental conditions at the single-cell level. This technology is expected to work as an in vitro model for fundamental research or pre-clinical drug development.

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Microfluidic Evolution Accelerator

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