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Planar Gradient Diffusion System to Investigate Chemotaxis in a 3D Collagen Matrix

DOI :

10.3791/52948-v

June 12th, 2015

June 12th, 2015

8,379 Views

1Department of Mechanical and Aerospace Engineering, California State University, Long Beach, 2Ximedica, 3School of Engineering, Brown University

Cell migration is an important part of human development and life. In order to understand the mechanisms that can alter cell migration, we present a planar gradient diffusion system to investigate chemotaxis in a 3D collagen matrix, which allows one to overcome modern diffusion chamber limitations of existing assays.

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Keywords Cell Migration

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