JoVE Logo
Faculty Resource Center

Sign In

Engineered 3D Silk-collagen-based Model of Polarized Neural Tissue

DOI :

10.3791/52970-v

6:17 min

October 23rd, 2015

October 23rd, 2015

12,120 Views

1Department of Biomedical Engineering, Tufts University, 2Department of Pediatrics, University of Connecticut Health Center & Connecticut Children's Medical Center

Insight into the complex actions of the brain requires advanced research tools. Here we demonstrate a novel silk-collagen-based 3D engineered model of neural tissue resembling brain-like architecture. The model can be used to study neuronal network assembly, axonal guidance, cell-cell interactions and electrical activity.

Tags

3D Silk collagen based Model

-- Views

Related Videos

article

Electric Field-controlled Directed Migration of Neural Progenitor Cells in 2D and 3D Environments

article

Magnetic Resonance Elastography Methodology for the Evaluation of Tissue Engineered Construct Growth

article

Protocol for Relative Hydrodynamic Assessment of Tri-leaflet Polymer Valves

article

Tissue Engineering of a Human 3D in vitro Tumor Test System

article

Generation and Grafting of Tissue-engineered Vessels in a Mouse Model

article

Production, Characterization and Potential Uses of a 3D Tissue-engineered Human Esophageal Mucosal Model

article

A Combined 3D Tissue Engineered In Vitro/In Silico Lung Tumor Model for Predicting Drug Effectiveness in Specific Mutational Backgrounds

article

Bioprinting of Cartilage and Skin Tissue Analogs Utilizing a Novel Passive Mixing Unit Technique for Bioink Precellularization

article

Seeding and Implantation of a Biosynthetic Tissue-engineered Tracheal Graft in a Mouse Model

article

Tissue-Engineered Graft for Circumferential Esophageal Reconstruction in Rats

JoVE Logo

Privacy

Terms of Use

Policies

Research

Education

ABOUT JoVE

Copyright © 2024 MyJoVE Corporation. All rights reserved