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Genome-wide Mapping of Drug-DNA Interactions in Cells with COSMIC (Crosslinking of Small Molecules to Isolate Chromatin)

8.1K Views

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10:05 min

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January 20th, 2016

DOI :

10.3791/53510-v

January 20th, 2016

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8,125 Views

Graham S. Erwin¹, Matthew P. Grieshop¹, Devesh Bhimsaria¹^,², Asuka Eguchi³, José A. Rodríguez-Martínez¹, Aseem Z. Ansari¹^,⁴

¹Department of Biochemistry, University of Wisconsin–Madison, ²Department of Electrical and Computer Engineering, University of Wisconsin–Madison, ³Graduate Program in Cellular and Molecular Biology, University of Wisconsin–Madison, ⁴The Genome Center, University of Wisconsin–Madison

Chapters

Transcript

Summary

Explore More Videos

Genome wide Mapping

Drug DNA Interactions

Small Molecules

Mechanism Of Action

Therapeutic Agents

DNA targeting Molecules

Pluripotent Stem Cells

Photo cross linking

Cell Dissociation

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