JoVE Logo
Faculty Resource Center

Sign In

A Rat Carotid Balloon Injury Model to Test Anti-vascular Remodeling Therapeutics

DOI :

10.3791/53777-v

September 19th, 2016

September 19th, 2016

8,521 Views

1Laboratory of Cardiovascular Sciences, National Institute on Aging, 2Department of Biomedical Science and Research Institute for Bioscience and Biotechnology, Hallym University

The rat carotid balloon injury model described below allows researchers to evaluate drugs or therapeutics that negate injury-induced arterial hyperplasia. Detailed pre-surgical preparation, surgical procedure, and post-surgical cares of the animal are described.

Tags

Rat Carotid Balloon Injury Model

-- Views

Related Videos

article

Rat Model of Blood-brain Barrier Disruption to Allow Targeted Neurovascular Therapeutics

article

Carotid Artery Infusions for Pharmacokinetic and Pharmacodynamic Analysis of Taxanes in Mice

article

Vascular Balloon Injury and Intraluminal Administration in Rat Carotid Artery

article

Retroductal Submandibular Gland Instillation and Localized Fractionated Irradiation in a Rat Model of Salivary Hypofunction

article

The Rabbit Model of Accelerated Atherosclerosis: A Methodological Perspective of the Iliac Artery Balloon Injury

article

Balloon-based Injury to Induce Myointimal Hyperplasia in the Mouse Abdominal Aorta

article

A Drosophila In Vivo Injury Model for Studying Neuroregeneration in the Peripheral and Central Nervous System

article

Ferric Chloride-induced Canine Carotid Artery Thrombosis: A Large Animal Model of Vascular Injury

article

A Rat Carotid Artery Pressure-Controlled Segmental Balloon Injury with Periadventitial Therapeutic Application

article

A Rat Model of Pressure Overload Induced Moderate Remodeling and Systolic Dysfunction as Opposed to Overt Systolic Heart Failure

JoVE Logo

Privacy

Terms of Use

Policies

Research

Education

ABOUT JoVE

Copyright © 2024 MyJoVE Corporation. All rights reserved