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Vascular Balloon Injury and Intraluminal Administration in Rat Carotid Artery

DOI :

10.3791/52045-v

December 23rd, 2014

December 23rd, 2014

15,909 Views

1Nanobioscience, State University of New York College of Nanoscale Science and Engineering (SUNY CNSE)

This protocol uses a balloon catheter to cause an intraluminal injury on the rat carotid artery and henceforth elicit neointimal hyperplasia. This is a well-established model for studying the mechanisms of vascular remodeling in response to injury. It is also widely used to determine the validity of potential therapeutic approaches.

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