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Insights into the Interactions of Amino Acids and Peptides with Inorganic Materials Using Single-Molecule Force Spectroscopy

DOI :

10.3791/54975-v

March 6th, 2017

March 6th, 2017

7,862 Views

1Institute of Chemistry and The Center for Nanoscience and Nanotechnology, The Hebrew University of Jerusalem

Here we present a protocol to measure the force of interactions between a well-defined inorganic surface and either peptides or amino acids by single-molecule force spectroscopy measurements using an atomic force microscope (AFM). The information obtained from the measurement is important to better understand the peptide-inorganic material interphase.

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Single molecule Force Spectroscopy

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