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Investigating Single Molecule Adhesion by Atomic Force Spectroscopy

DOI :

10.3791/52456-v

February 27th, 2015

February 27th, 2015

10,008 Views

1Physik-Department E22a, Technische Universität München, 2IMETUM, Technische Universität München

A protocol to couple a large variety of single molecules covalently onto an AFM tip is presented. Procedures and examples to determine the adhesion force and free energy of these molecules on solid supports and bio-interfaces are provided.

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