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A High-throughput Compatible Assay to Evaluate Drug Efficacy against Macrophage Passaged Mycobacterium tuberculosis

DOI :

10.3791/55453-v

March 24th, 2017

March 24th, 2017

7,622 Views

1Department of Medicine, University of Alabama at Birmingham

New models and assays that would improve the early drug development process for next-generation anti-tuberculosis drugs are highly desirable. Here, we describe a quick, inexpensive, and BSL-2 compatible assay to evaluate drug efficacy against Mycobacterium tuberculosis that can be easily adapted for high-throughput screening.

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Keywords Macrophage

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