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Modeling Tuberculosis in Mycobacterium marinum Infected Adult Zebrafish

DOI :

10.3791/58299-v

October 8th, 2018

October 8th, 2018

9,979 Views

1Faculty of Medicine and Life Sciences, University of Tampere, 2Oral and Maxillofacial Unit, Tampere University Hospital

Here, we present a protocol to model human tuberculosis in an adult zebrafish using its natural pathogen Mycobacterium marinum. Extracted DNA and RNA from the internal organs of infected zebrafish can be used to reveal the total mycobacterial loads in the fish and the host's immune responses with qPCR.

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