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Assessment of Long-term Depression Induction in Adult Cerebellar Slices

DOI :

10.3791/59859-v

October 16th, 2019

October 16th, 2019

6,709 Views

1Laboratory for Behavioral Genetics, Center for Brain Science, RIKEN, 2Senior Adviser's Office, Center for Brain Science, RIKEN

In some gene-manipulated animals, using a single protocol may fail to induce LTD in cerebellar Purkinje cells, and there may be a discrepancy between LTD and motor learning. Multiple protocols are necessary to assess LTD-induction in gene-manipulated animals. Standard protocols are shown.

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Keywords LTD Induction

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