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In Vivo Assessment of Alveolar Macrophage Efferocytosis Following Ozone Exposure

DOI :

10.3791/60109-v

October 22nd, 2019

October 22nd, 2019

8,611 Views

1Department of Pharmacology and Toxicology, East Carolina University, 2Research Triangle Park, National Institute of Environmental Health and Sciences

This manuscript describes a protocol for determining whether exposure to ozone, a criteria air pollutant, impairs alveolar macrophage efferocytosis in vivo. This protocol utilizes commonly used reagents and techniques and can be adapted to multiple models of pulmonary injury to determine effects on alveolar macrophage efferocytosis.

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