Protocol: Chapter I. Ozone and LPS Exposures for Induction of Murine ALI
2:33
Protocol: Chapter II. Sample Collection
8:55
Protocol: Chapter III. Sample Processing
10:17
Representative Results
14:24
Conclusion
Transcript
Hi, my name is Gurpreet. Our lab investigates mechanisms of lung inflammation and repair. Hi, my name is Jessica and I investigate ozone-induced lab rat alveoli by using fluorescent microscopic methods.
Hello everyone, my name is Manpreet. A
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Combined ozone and bacterial endotoxin exposed mice show wide-spread cell death, including that of neutrophils. We observed cellular adaptations such as disruption of cytoskeletal lamellipodia, increased cellular expression of complex V ATP synthase subunit β and angiostatin in broncho-alveolar lavage, suppression of the lung immune response and delayed neutrophil recruitment.