September 9th, 2020
•Bone metastasis models do not develop metastasis uniformly or with a 100% incidence. Direct intra-osseous tumor cell injection can result in embolization of the lung. We present our technique modeling primary bone tumors and bone metastasis using solid tumor graft implantation into bone, leading to reproducible engraftment and growth.
Tags
Related Videos
Next Generation Sequencing for the Detection of Actionable Mutations in Solid and Liquid Tumors
Intra-iliac Artery Injection for Efficient and Selective Modeling of Microscopic Bone Metastasis
Dual Effects of Melanoma Cell-derived Factors on Bone Marrow Adipocytes Differentiation
Multimodal Bioluminescent and Positronic-emission Tomography/Computational Tomography Imaging of Multiple Myeloma Bone Marrow Xenografts in NOG Mice
Measuring Bone Remodeling and Recreating the Tumor-Bone Microenvironment Using Calvaria Co-culture and Histomorphometry
Three-Dimensional Bone Extracellular Matrix Model for Osteosarcoma
Micromanipulation of Circulating Tumor Cells for Downstream Molecular Analysis and Metastatic Potential Assessment
Establishment and Analysis of Three-Dimensional (3D) Organoids Derived from Patient Prostate Cancer Bone Metastasis Specimens and their Xenografts
Machine Learning Algorithms for Early Detection of Bone Metastases in an Experimental Rat Model
Intra-Cardiac Injection of Human Prostate Cancer Cells to Create a Bone Metastasis Xenograft Mouse Model
ABOUT JoVE
Copyright © 2024 MyJoVE Corporation. All rights reserved