A Chronic Sleep Fragmentation Model using Vibrating Orbital Rotor to Induce Cognitive Deficit and Anxiety-Like Behavior in Young Wild-Type Mice
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06:23 min
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September 22nd, 2020
DOI :
September 22nd, 2020
•Yi Xie1, Sai-Yue Deng1, Si-Miao Chen1, Xue-Jiao Chen1, Wen-Wen Lai1, Li-Fang Huang1, Li Ba1, Wei Wang1,2, Feng-Fei Ding1,3
1Department of Neurology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430000, China, 2Key Laboratory of Neurological Diseases of Chinese Ministry of Education, The School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430000,China, 3Department of Pharmacology, School of Basic Medical Science; State Key Laboratory of Medical Neurobiology, Institutes of Brain Science and Collaborative Innovation Center for Brain Science, Fudan University, Shanghai 200032, China
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Chapters in this video
0:04
Introduction
1:06
Mouse Screening Preparation
1:58
Chronic Sleep Fragmentation (CSF) Modeling
3:04
Morris Water Maze (MWM) Test
4:00
Results: Representative Effects of CSF Modeling on Young Wild-Type Mouse Cognitive Abilities and Anxiety-Like Behaviors
5:34
Conclusion
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