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The Establishment and Utilization of Patient Derived Xenograft Models of Central Nervous System Metastasis

DOI :

10.3791/62264-v

6:52 min

May 7th, 2021

May 7th, 2021

1,753 Views

1Department of Translational Genomics, Keck School of Medicine, University of Southern California

Central nervous system metastasis PDX models represent the phenotypic and molecular characteristics of human metastasis, making them excellent models for preclinical studies. Described here is how to establish PDX models and the inoculation routes that are best used for preclinical studies.

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Patient derived Xenograft Models

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