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A Melanoma Patient-Derived Xenograft Model

DOI :

10.3791/59508-v

May 20th, 2019

May 20th, 2019

11,806 Views

1Wistar Institute

Patient-derived xenograft (PDX) models more robustly recapitulate melanoma molecular and biological features and are more predictive of therapy response compared to traditional plastic tissue culture-based assays. Here we describe our standard operating protocol for the establishment of new PDX models and the characterization/experimentation of existing PDX models.

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Melanoma

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