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A Microfluidics Approach for the Functional Investigation of Signaling Oscillations Governing Somitogenesis

DOI :

10.3791/62318-v

8:06 min

March 19th, 2021

March 19th, 2021

2,379 Views

1Hubrecht Institute-KNAW (Royal Netherlands Academy of Arts and Sciences) and University Medical Center Utrecht

A protocol for the culture and manipulation of mouse embryonic tissue on a microfluidic chip is provided. By applying pulses of pathway modulators, this system can be used to externally control signaling oscillations for the functional investigation of mouse somitogenesis.

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Microfluidics Approach

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